National Institute on Alcohol Abuse and Alcoholism Publications ( 110 ) Lang CH. Frost RA. Vary TC. Skeletal muscle protein synthesis and degradation exhibit sexual dimorphism after chronic alcohol consumption but not acute intoxication. 2007 Jun. Am J Physiol Endocrinol Metab. 292(6):E1497-506. National Institute on Alcohol Abuse and Alcoholism Page JL. Johnson MC. Olsavsky KM. Strom SC. Zarbl H. Omiecinski CJ. Gene expression profiling of extracellular matrix as an effector of human hepatocyte phenotype in primary cell culture. 2007 Jun. Toxicol Sci. 97(2):384-97. National Institute on Aging National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Neurological Disorders and Stroke National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences National Institute of Environmental Health Sciences Grandey AA. Kern JH. Frone MR. Verbal abuse from outsiders versus insiders: comparing frequency, impact on emotional exhaustion, and the role of emotional labor. 2007 Jan. J Occup Health Psychol. 12(1):63-79. National Institute on Alcohol Abuse and Alcoholism Blizard DA. Sweet and bitter taste of ethanol in C57BL/6J and DBA2/J mouse strains. 2007 Jan. Behav Genet. 37(1):146-59. National Institute on Alcohol Abuse and Alcoholism National Institute on Deafness and other Communication Disorders Hong-Brown LQ. Brown CR. Huber DS. Lang CH. Alcohol regulates eukaryotic elongation factor 2 phosphorylation via an AMP-activated protein kinase-dependent mechanism in C2C12 skeletal myocytes. 2007 Feb 9. J Biol Chem. 282(6):3702-12. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases Vary TC. Kimball SR. Sumner A. Sex-dependent differences in the regulation of myocardial protein synthesis following long-term ethanol consumption. 2007 Feb. Am J Physiol Regul Integr Comp Physiol. 292(2):R778-87. National Institute on Alcohol Abuse and Alcoholism Chuang CH. Liebschutz JM. Cheng DM. Raj A. Samet JH. Substance use during sexual and physical assault in HIV-infected persons. 2007. Violence Vict. 22(2):216-25. National Institute on Alcohol Abuse and Alcoholism Krasilnikova MM. Kireeva ML. Petrovic V. Knijnikova N. Kashlev M. Mirkin SM. Effects of Friedreich's ataxia (GAA)n*(TTC)n repeats on RNA synthesis and stability. 2007. Nucleic Acids Res. 35(4):1075-84. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Cortese BM. Moore GJ. Bailey BA. Jacobson SW. Delaney-Black V. Hannigan JH. Magnetic resonance and spectroscopic imaging in prenatal alcohol-exposed children: preliminary findings in the caudate nucleus. 2006 Sep-Oct. Neurotoxicol Teratol. 28(5):597-606. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Vary TC. Lynch CJ. Meal feeding stimulates phosphorylation of multiple effector proteins regulating protein synthetic processes in rat hearts. 2006 Sep. J Nutr. 136(9):2284-90. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Lang CH. Elevated plasma free fatty acids decrease basal protein synthesis, but not the anabolic effect of leucine, in skeletal muscle. 2006 Sep. Am J Physiol Endocrinol Metab. 291(3):E666-74. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Lynch CJ. Gern B. Lloyd C. Hutson SM. Eicher R. Vary TC. Leucine in food mediates some of the postprandial rise in plasma leptin concentrations. 2006 Sep. Am J Physiol Endocrinol Metab. 291(3):E621-30. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Turrisi R. Mallett KA. Mastroleo NR. Larimer ME. Heavy drinking in college students: who is at risk and what is being done about it? 2006 Oct. J Gen Psychol. 133(4):401-20. National Institute on Alcohol Abuse and Alcoholism Freeman WM. Gooch RS. Lull ME. Worst TJ. Walker SJ. Xu AS. Green H. Pierre PJ. Grant KA. Vrana KE. Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration. 2006 May-Jun. Alcohol Alcohol. 41(3):300-5. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Hong-Brown LQ. Brown CR. Huber DS. Lang CH. Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes. 2006 Aug. Alcohol Clin Exp Res. 30(8):1297-307. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases Hong-Brown LQ. Pruznak AM. Frost RA. Vary TC. Lang CH. Indinavir alters regulators of protein anabolism and catabolism in skeletal muscle. 2005 Sep. Am J Physiol Endocrinol Metab. 289(3):E382-90. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Crozier SJ. Vary TC. Kimball SR. Jefferson LS. Cellular energy status modulates translational control mechanisms in ischemic-reperfused rat hearts. 2005 Sep. Am J Physiol Heart Circ Physiol. 289(3):H1242-50. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Ridenour TA. Maldonado-Molina M. Compton WM. Spitznagel EL. Cottler LB. Factors associated with the transition from abuse to dependence among substance abusers: implications for a measure of addictive liability. 2005 Oct 1. Drug Alcohol Depend. 80(1):1-14. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse National Institute of Mental Health Lang CH. Frost RA. Summer AD. Vary TC. Molecular mechanisms responsible for alcohol-induced myopathy in skeletal muscle and heart. 2005 Oct. Int J Biochem Cell Biol. 37(10):2180-95. National Institute on Alcohol Abuse and Alcoholism Hong-Brown LQ. Brown CR. Lang CH. HIV antiretroviral agents inhibit protein synthesis and decrease ribosomal protein S6 and 4EBP1 phosphorylation in C2C12 myocytes. 2005 Oct. AIDS Res Hum Retroviruses. 21(10):854-62. National Institute on Alcohol Abuse and Alcoholism Frost RA. Nystrom G. Burrows PV. Lang CH. Temporal differences in the ability of ethanol to modulate endotoxin-induced increases in inflammatory cytokines in muscle under in vivo conditions. 2005 Jul. Alcohol Clin Exp Res. 29(7):1247-56. National Institute on Alcohol Abuse and Alcoholism Vary TC. Deiter G. Goodman SA. Acute alcohol intoxication enhances myocardial eIF4G phosphorylation despite reducing mTOR signaling. 2005 Jan. Am J Physiol Heart Circ Physiol. 288(1):H121-8. National Institute on Alcohol Abuse and Alcoholism Vary TC. Deiter G. Long-term alcohol administration inhibits synthesis of both myofibrillar and sarcoplasmic proteins in heart. 2005 Feb. Metabolism. 54(2):212-9. National Institute on Alcohol Abuse and Alcoholism Vary TC. Lang CH. IGF-I activates the eIF4F system in cardiac muscle in vivo. 2005 Apr. Mol Cell Biochem. 272(1-2):209-20. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences National Heart, Lung, and Blood Institute Gallagher SF. Peng Y. Haines K. Baksh K. Epling-Burnette PK. Yang J. Murr MM. Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosis. 2005 Apr. J Gastrointest Surg. 9(4):467-74; discussion 474-5. National Institute on Alcohol Abuse and Alcoholism Maggs JL. Schulenberg JE. Initiation and course of alcohol consumption among adolescents and young adults. 2005. Recent Dev Alcohol. 17:29-47. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse National Institute of Mental Health Lang CH. Pruznak AM. Deshpande N. Palopoli MM. Frost RA. Vary TC. Alcohol intoxication impairs phosphorylation of S6K1 and S6 in skeletal muscle independently of ethanol metabolism. 2004 Nov. Alcohol Clin Exp Res. 28(11):1758-67. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Hong-Brown LQ. Brown CR. Lang CH. Indinavir impairs protein synthesis and phosphorylations of MAPKs in mouse C2C12 myocytes. 2004 Nov. Am J Physiol Cell Physiol. 287(5):C1482-92. National Institute on Alcohol Abuse and Alcoholism Frost RA. Nystrom GJ. Lang CH. Epinephrine stimulates IL-6 expression in skeletal muscle and C2C12 myoblasts: role of c-Jun NH2-terminal kinase and histone deacetylase activity. 2004 May. Am J Physiol Endocrinol Metab. 286(5):E809-17. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Lang CH. Frost RA. Svanberg E. Vary TC. IGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed rats. 2004 Jun. Am J Physiol Endocrinol Metab. 286(6):E916-26. National Institute on Alcohol Abuse and Alcoholism Yang J. Gallagher SF. Haines K. Epling-Burnette PK. Bai F. Gower WR. Mastorides S. Norman JG. Murr MM. Kupffer cell-derived Fas ligand plays a role in liver injury and hepatocyte death. 2004 Feb. J Gastrointest Surg. 8(2):166-74. National Institute on Alcohol Abuse and Alcoholism Gallagher SF. Yang J. Baksh K. Haines K. Carpenter H. Epling-Burnette PK. Peng Y. Norman J. Murr MM. Acute pancreatitis induces FasL gene expression and apoptosis in the liver. 2004 Dec. J Surg Res. 122(2):201-9. National Institute on Alcohol Abuse and Alcoholism Vary TC. Nairn AC. Lang CH. Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol. 2004 Apr. Alcohol Clin Exp Res. 28(4):517-25. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Lang CH. Vary TC. Frost RA. Acute in vivo elevation of insulin-like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesis. 2003 Sep. Endocrinology. 144(9):3922-33. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Frost RA. Nystrom GJ. Lang CH. Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH2-terminal kinase. 2003 Nov. Am J Physiol Regul Integr Comp Physiol. 285(5):R1153-64. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Ridenour TA. Cottler LB. Compton WM. Spitznagel EL. Cunningham-Williams RM. Is there a progression from abuse disorders to dependence disorders? 2003 May. Addiction. 98(5):635-44. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse National Institute of Mental Health Frost RA. Nystrom GJ. Lang CH. Tumor necrosis factor-alpha decreases insulin-like growth factor-I messenger ribonucleic acid expression in C2C12 myoblasts via a Jun N-terminal kinase pathway. 2003 May. Endocrinology. 144(5):1770-9. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Frost RA. Lang CH. Regulation of insulin-like growth factor-I in skeletal muscle and muscle cells. 2003 Mar. Minerva Endocrinol. 28(1):53-73. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Lang CH. Frost RA. Deshpande N. Kumar V. Vary TC. Jefferson LS. Kimball SR. Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle. 2003 Dec. Am J Physiol Endocrinol Metab. 285(6):E1205-15. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Worst TJ. Freeman WM. Walker SJ. Vrana KE. Systematic screening of gene expression using a cDNA macroarray. 2003. Methods Mol Med. 79:243-59. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Frost RA. Nystrom GJ. Lang CH. Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle. 2002 Sep. Am J Physiol Regul Integr Comp Physiol. 283(3):R698-709. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Lynch CJ. Patson BJ. Anthony J. Vaval A. Jefferson LS. Vary TC. Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue. 2002 Sep. Am J Physiol Endocrinol Metab. 283(3):E503-13. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences McClearn GE. Genetics of behavioral aging: animal models and the human condition. 2002 Oct-Dec. Exp Aging Res. 28(4):453-76. National Institute on Alcohol Abuse and Alcoholism National Institute on Aging Kumar V. Silvis C. Nystrom G. Deshpande N. Vary TC. Frost RA. Lang CH. Alcohol-induced increases in insulin-like growth factor binding protein-1 are partially mediated by TNF. 2002 Oct. Alcohol Clin Exp Res. 26(10):1574-83. National Institute on Alcohol Abuse and Alcoholism Lynch CJ. Hutson SM. Patson BJ. Vaval A. Vary TC. Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats. 2002 Oct. Am J Physiol Endocrinol Metab. 283(4):E824-35. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Kumar V. Frost RA. Lang CH. Alcohol impairs insulin and IGF-I stimulation of S6K1 but not 4E-BP1 in skeletal muscle. 2002 Nov. Am J Physiol Endocrinol Metab. 283(5):E917-28. National Institute on Alcohol Abuse and Alcoholism Cibelli JB. Grant KA. Chapman KB. Cunniff K. Worst T. Green HL. Walker SJ. Gutin PH. Vilner L. Tabar V. Dominko T. Kane J. Wettstein PJ. Lanza RP. Studer L. Vrana KE. West MD. Parthenogenetic stem cells in nonhuman primates. 2002 Feb 1. Science. 295(5556):819. National Institute on Alcohol Abuse and Alcoholism Frost RA. Nystrom GJ. Lang CH. Regulation of IGF-I mRNA and signal transducers and activators of transcription-3 and -5 (Stat-3 and -5) by GH in C2C12 myoblasts. 2002 Feb. Endocrinology. 143(2):492-503. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Lang CH. Frost RA. Nairn AC. MacLean DA. Vary TC. TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation. 2002 Feb. Am J Physiol Endocrinol Metab. 282(2):E336-47. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences National Heart, Lung, and Blood Institute Vary TC. Nairn AC. Deiter G. Lang CH. Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver. 2002 Dec. Alcohol Clin Exp Res. 26(12):1794-802. National Institute on Alcohol Abuse and Alcoholism Hong-Brown LQ. Frost RA. Lang CH. Alcohol impairs protein synthesis and degradation in cultured skeletal muscle cells. 2001 Sep. Alcohol Clin Exp Res. 25(9):1373-82. National Institute on Alcohol Abuse and Alcoholism Vary TC. Lynch CJ. Lang CH. Effects of chronic alcohol consumption on regulation of myocardial protein synthesis. 2001 Sep. Am J Physiol Heart Circ Physiol. 281(3):H1242-51. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases Lang CH. Kimball SR. Frost RA. Vary TC. Alcohol myopathy: impairment of protein synthesis and translation initiation. 2001 May. Int J Biochem Cell Biol. 33(5):457-73. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases Reed CL. Hood KE. Cortes DA. Jones BC. Genetic-environment analysis of sensitivity and acute tolerance to ethanol in mice. 2001 Jul-Aug. Pharmacol Biochem Behav. 69(3-4):461-7. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Lang CH. Nystrom GJ. Frost RA. Tissue-specific regulation of IGF-I and IGF-binding proteins in response to TNFalpha. 2001 Aug. Growth Horm IGF Res. 11(4):250-60. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences National Heart, Lung, and Blood Institute Walker SJ. Grant KA. Vrana KE. Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse. 2001 Aug. Alcohol Clin Exp Res. 25(8):1114-8. National Institute on Alcohol Abuse and Alcoholism Frost RA. Nystrom GJ. Lang CH. Stimulation of insulin-like growth factor binding protein-1 synthesis by interleukin-1beta: requirement of the mitogen-activated protein kinase pathway. 2000 Sep. Endocrinology. 141(9):3156-64. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Lang CH. Frost RA. Kumar V. Vary TC. Impaired myocardial protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4F. 2000 Nov. Am J Physiol Endocrinol Metab. 279(5):E1029-38. National Institute on Alcohol Abuse and Alcoholism Freeman WM. Robertson DJ. Vrana KE. Fundamentals of DNA hybridization arrays for gene expression analysis. 2000 Nov. Biotechniques. 29(5):1042-6, 1048-55. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Lang CH. Liu X. Nystrom G. Wu D. Cooney RN. Frost RA. Acute effects of growth hormone in alcohol-fed rats. 2000 Mar-Apr. Alcohol Alcohol. 35(2):148-58. National Institute on Alcohol Abuse and Alcoholism Lang CH. Frost RA. Kumar V. Wu D. Vary TC. Impaired protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4E in muscle and eIF2B in liver. 2000 Mar. Alcohol Clin Exp Res. 24(3):322-31. National Institute on Alcohol Abuse and Alcoholism Blizard DA. McClearn GE. Association between ethanol and sucrose intake in the laboratory mouse: exploration via congenic strains and conditioned taste aversion. 2000 Mar. Alcohol Clin Exp Res. 24(3):253-8. National Institute on Alcohol Abuse and Alcoholism National Institute on Deafness and other Communication Disorders Yohrling GJ. Jiang GC. Mockus SM. Vrana KE. Intersubunit binding domains within tyrosine hydroxylase and tryptophan hydroxylase. 2000 Aug 1. J Neurosci Res. 61(3):313-20. National Institute of General Medical Sciences National Institute on Alcohol Abuse and Alcoholism McClearn GE. Vandenbergh DJ. Structures and limits of animal models: examples from alcohol research. 2000. ILAR J. 41(3):144-52. National Institute on Alcohol Abuse and Alcoholism Blackson TC. Butler T. Belsky J. Ammerman RT. Shaw DS. Tarter RE. Individual traits and family contexts predict sons' externalizing behavior and preliminary relative risk ratios for conduct disorder and substance use disorder outcomes. 1999 Sep 1. Drug Alcohol Depend. 56(2):115-31. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Frost RA. Lang CH. Differential effects of insulin-like growth factor I (IGF-I) and IGF-binding protein-1 on protein metabolism in human skeletal muscle cells. 1999 Sep. Endocrinology. 140(9):3962-70. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Jones BC. Tarantino LM. Rodriguez LA. Reed CL. McClearn GE. Plomin R. Erwin VG. Quantitative-trait loci analysis of cocaine-related behaviours and neurochemistry. 1999 Oct. Pharmacogenetics. 9(5):607-17. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Lang CH. Wu D. Frost RA. Jefferson LS. Vary TC. Kimball SR. Chronic alcohol feeding impairs hepatic translation initiation by modulating eIF2 and eIF4E. 1999 Nov. Am J Physiol. 277(5 Pt 1):E805-14. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases Lang CH. Nystrom GJ. Frost RA. Regulation of IGF binding protein-1 in hep G2 cells by cytokines and reactive oxygen species. 1999 Mar. Am J Physiol. 276(3 Pt 1):G719-27. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Yohrling GJ. Mockus SM. Vrana KE. Identification of amino-terminal sequences contributing to tryptophan hydroxylase tetramer formation. 1999 Feb. J Mol Neurosci. 12(1):23-34. National Institute of General Medical Sciences National Institute on Alcohol Abuse and Alcoholism Fernandez JR. Vogler GP. Tarantino LM. Vignetti S. Plomin R. McClearn GE. Sex-exclusive quantitative trait loci influences in alcohol-related phenotypes. 1999 Dec 15. Am J Med Genet. 88(6):647-52. National Institute on Alcohol Abuse and Alcoholism National Institute of Child Health and Human Development Lang CH. Wu D. Frost RA. Jefferson LS. Kimball SR. Vary TC. Inhibition of muscle protein synthesis by alcohol is associated with modulation of eIF2B and eIF4E. 1999 Aug. Am J Physiol. 277(2 Pt 1):E268-76. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases Palmer RF. Graham JW. White EL. Hansen WB. Applying multilevel analytic strategies in adolescent substance use prevention research. 1998 May-Jun. Prev Med. 27(3):328-36. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Frost RA. Lang CH. Growth factors in critical illness: regulation and therapeutic aspects. 1998 Mar. Curr Opin Clin Nutr Metab Care. 1(2):195-204. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Cook MN. Ware DD. Boone EM. Hou X. Morse AC. Reed CL. Erwin VG. Jones BC. Ethanol modulates cocaine-induced behavioral change in inbred mice. 1998 Mar. Pharmacol Biochem Behav. 59(3):567-75. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Lang CH. Fan J. Lipton BP. Potter BJ. McDonough KH. Modulation of the insulin-like growth factor system by chronic alcohol feeding. 1998 Jun. Alcohol Clin Exp Res. 22(4):823-9. National Institute on Alcohol Abuse and Alcoholism Mockus SM. Vrana KE. Advances in the molecular characterization of tryptophan hydroxylase. 1998 Jun. J Mol Neurosci. 10(3):163-79. National Institute of General Medical Sciences National Institute on Alcohol Abuse and Alcoholism Jones BC. Sarrieau A. Reed CL. Azar MR. Mormède P. Contribution of sex and genetics to neuroendocrine adaptation to stress in mice. 1998 Jul. Psychoneuroendocrinology. 23(5):505-17. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Mockus SM. Yohrling GJ. Vrana KE. Tyrosine hydroxylase and tryptophan hydroxylase do not form heterotetramers. 1998 Feb. J Mol Neurosci. 10(1):45-51. National Institute of General Medical Sciences National Institute on Alcohol Abuse and Alcoholism McClearn GE. Tarantino LM. Hofer SM. Jones B. Plomin R. Developmental loss of effect of a Chromosome 15 QTL on alcohol acceptance. 1998 Dec. Mamm Genome. 9(12):991-4. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Tarantino LM. McClearn GE. Rodriguez LA. Plomin R. Confirmation of quantitative trait loci for alcohol preference in mice. 1998 Aug. Alcohol Clin Exp Res. 22(5):1099-105. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse McClearn GE. Tarantino LM. Rodriguez LA. Jones BC. Blizard DA. Plomin R. Genotypic selection provides experimental confirmation for an alcohol consumption quantitative trait locus in mouse. 1997 Oct-Nov. Mol Psychiatry. 2(6):486-9. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Mockus SM. Kumer SC. Vrana KE. Carboxyl terminal deletion analysis of tryptophan hydroxylase. 1997 Oct 17. Biochim Biophys Acta. 1342(2):132-40. National Institute of General Medical Sciences National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Frost RA. Lang CH. Gelato MC. Transient exposure of human myoblasts to tumor necrosis factor-alpha inhibits serum and insulin-like growth factor-I stimulated protein synthesis. 1997 Oct. Endocrinology. 138(10):4153-9. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Kumer SC. Mockus SM. Rucker PJ. Vrana KE. Amino-terminal analysis of tryptophan hydroxylase: protein kinase phosphorylation occurs at serine-58. 1997 Oct. J Neurochem. 69(4):1738-45. National Institute of General Medical Sciences National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Boone EM. Cook MN. Hou X. Jones BC. Sex and strain influence the effect of ethanol on central monoamines. 1997 Nov. J Stud Alcohol. 58(6):590-9. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse van de Pavert SA. Clarke IJ. Rao A. Vrana KE. Schwartz J. Effects of vasopressin and elimination of corticotropin-releasing hormone-target cells on pro-opiomelanocortin mRNA levels and adrenocorticotropin secretion in ovine anterior pituitary cells. 1997 Jul. J Endocrinol. 154(1):139-47. National Institute on Alcohol Abuse and Alcoholism Lang CH. Pollard V. Fan J. Traber LD. Traber DL. Frost RA. Gelato MC. Prough DS. Acute alterations in growth hormone-insulin-like growth factor axis in humans injected with endotoxin. 1997 Jul. Am J Physiol. 273(1 Pt 2):R371-8. National Institute on Alcohol Abuse and Alcoholism National Institute of General Medical Sciences Mockus SM. Kumer SC. Vrana KE. A chimeric tyrosine/tryptophan hydroxylase. The tyrosine hydroxylase regulatory domain serves to stabilize enzyme activity. 1997 Aug. J Mol Neurosci. 9(1):35-48. National Institute of General Medical Sciences National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Milakofsky L. Harris N. Vogel WH. Effect of repeated stress on a number of plasma amino acids and related compounds in young and old rats. 1996 Sep. Physiol Behav. 60(3):969-71. National Institute on Alcohol Abuse and Alcoholism Samstein B. Hoimes ML. Fan J. Frost RA. Gelato MC. Lang CH. IL-6 stimulation of insulin-like growth factor binding protein (IGFBP)-1 production. 1996 Nov 12. Biochem Biophys Res Commun. 228(2):611-5. National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Jones BC. Hou X. Cook MN. Effect of exposure to novelty on brain monoamines in C57BL/6 and DBA/2 mice. 1996 Feb. Physiol Behav. 59(2):361-7. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse McClearn GE. Vogler GP. Plomin R. Genetics and behavioral medicine. 1996. Behav Med. 22(3):93-102. National Institute on Alcohol Abuse and Alcoholism National Institute on Aging National Institute on Drug Abuse Morse AC. Erwin VG. Jones BC. Behavioral responses to low doses of cocaine are affected by genetics and experimental history. 1995 Nov. Physiol Behav. 58(5):891-7. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Rodriguez LA. Plomin R. Blizard DA. Jones BC. McClearn GE. Alcohol acceptance, preference, and sensitivity in mice. II. Quantitative trait loci mapping analysis using BXD recombinant inbred strains. 1995 Apr. Alcohol Clin Exp Res. 19(2):367-73. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse McClearn GE. Sex distinctiveness in effective genotype. 1995. Recent Dev Alcohol. 12:217-21. National Institute on Alcohol Abuse and Alcoholism Rodriguez LA. Plomin R. Blizard DA. Jones BC. McClearn GE. Alcohol acceptance, preference, and sensitivity in mice. I. Quantitative genetic analysis using BXD recombinant inbred strains. 1994 Dec. Alcohol Clin Exp Res. 18(6):1416-22. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse McClearn GE. Jones B. Blizard DA. Plomin R. The utilization of quantitative trait loci in toxicogenetics. 1993 Sep. J Exp Anim Sci. 35(5-6):251-8. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Milakofsky L. Harris N. Vogel WH. Effects of repeated stress on plasma arginine levels in young and old rats. 1993 Oct. Physiol Behav. 54(4):725-8. National Institute on Alcohol Abuse and Alcoholism Plomin R. McClearn GE. Quantitative trait loci (QTL) analyses and alcohol-related behaviors. 1993 Mar. Behav Genet. 23(2):197-211. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Milakofsky L. Harris N. Vogel WH. Effect of repeated stress on plasma catecholamines and taurine in young and old rats. 1993 Jul-Aug. Neurobiol Aging. 14(4):359-66. National Institute on Alcohol Abuse and Alcoholism Vogt BL. Richie JP. Fasting-induced depletion of glutathione in the aging mouse. 1993 Jul 20. Biochem Pharmacol. 46(2):257-63. National Institute on Alcohol Abuse and Alcoholism Kenkel DS. Do drunk drivers pay their way? A note on optimal penalties for drunk driving. 1993 Jul. J Health Econ. 12(2):137-49. National Institute on Alcohol Abuse and Alcoholism Jones BC. Reed CL. Radcliffe RA. Erwin VG. Pharmacogenetics of cocaine: I. Locomotor activity and self-selection. 1993 Aug. Pharmacogenetics. 3(4):182-8. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Blizard DA. Recombinant-inbred strains: general methodological considerations relevant to the study of complex characters. 1992 Nov. Behav Genet. 22(6):621-33. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Blizard DA. Recombinant-inbred strains: application to behavioral phenomena. 1992 Nov. Behav Genet. 22(6):615-9. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Plomin R. McClearn GE. Gora-Maslak G. Neiderhiser JM. Use of recombinant inbred strains to detect quantitative trait loci associated with behavior. 1991 Mar. Behav Genet. 21(2):99-116. National Institute on Alcohol Abuse and Alcoholism Jones BC. Campbell AD. Radcliffe RA. Erwin VG. Cocaine actions, brain levels and receptors in selected lines of mice. 1991 Dec. Pharmacol Biochem Behav. 40(4):941-8. National Institute on Alcohol Abuse and Alcoholism Gora-Maslak G. McClearn GE. Crabbe JC. Phillips TJ. Belknap JK. Plomin R. Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology. 1991. Psychopharmacology (Berl). 104(4):413-24. National Institute on Alcohol Abuse and Alcoholism Milakofsky L. Miller JM. Vogel WH. Effect of ethanol on plasma amino acids and related compounds of stressed male rats. 1989 Apr. Pharmacol Biochem Behav. 32(4):1071-4. National Institute on Alcohol Abuse and Alcoholism