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National Institute on Aging National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Neurological Disorders and Stroke National Institute on Alcohol Abuse and Alcoholism National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences National Institute of Environmental Health Sciences Olsavsky KM. Page JL. Johnson MC. Zarbl H. Strom SC. Omiecinski CJ. Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues. 2007 Jul 1. Toxicol Appl Pharmacol. 222(1):42-56. National Institute of General Medical Sciences National Institute of Environmental Health Sciences Patel RD. Hollingshead BD. Omiecinski CJ. Perdew GH. Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. 2007 Jul. Hepatology. 46(1):209-18. National Institute of Environmental Health Sciences National Institute of General Medical Sciences Morales JL. Perdew GH. Carboxyl terminus of hsc70-interacting protein (CHIP) can remodel mature aryl hydrocarbon receptor (AhR) complexes and mediate ubiquitination of both the AhR and the 90 kDa heat-shock protein (hsp90) in vitro. 2007 Jan 16. Biochemistry. 46(2):610-21. National Institute of Environmental Health Sciences Liu L. Watanabe K. Fang Q. Williams KM. Guengerich FP. Pegg AE. Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its ability to modulate the genotoxicity of 1,2-dibromoethane. 2007 Jan. Chem Res Toxicol. 20(1):155-63. National Institute of Environmental Health Sciences National Cancer Institute Taylor AB. Borhan A. Ultman JS. Three-dimensional simulations of reactive gas uptake in single airway bifurcations. 2007 Feb. Ann Biomed Eng. 35(2):235-49. National Institute of Environmental Health Sciences Haque R. Umstead TM. Ponnuru P. Guo X. Hawgood S. Phelps DS. Floros J. Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. 2007 Apr 1. Toxicol Appl Pharmacol. 220(1):72-82. National Institute of Environmental Health Sciences Liao D. Peuquet DJ. Duan Y. Whitsel EA. Dou J. Smith RL. Lin HM. Chen JC. Heiss G. GIS approaches for the estimation of residential-level ambient PM concentrations. 2006 Sep. Environ Health Perspect. 114(9):1374-80. National Institute of Environmental Health Sciences Patel RD. Kim DJ. Peters JM. Perdew GH. The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin. 2006 Jan. Toxicol Sci. 89(1):75-82. National Institute of Environmental Health Sciences Gray JP. Davis JW. Gopinathan L. Leas TL. Nugent CA. Vanden Heuvel JP. The ribosomal protein rpL11 associates with and inhibits the transcriptional activity of peroxisome proliferator-activated receptor-alpha. 2006 Feb. Toxicol Sci. 89(2):535-46. National Institute of Environmental Health Sciences Hollingshead BD. Patel RD. Perdew GH. Endogenous hepatic expression of the hepatitis B virus X-associated protein 2 is adequate for maximal association with aryl hydrocarbon receptor-90-kDa heat shock protein complexes. 2006 Dec. Mol Pharmacol. 70(6):2096-107. National Cancer Institute National Institute of Environmental Health Sciences Murray IA. Reen RK. Leathery N. Ramadoss P. Bonati L. Gonzalez FJ. Peters JM. Perdew GH. Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity. 2005 Oct 1. Arch Biochem Biophys. 442(1):59-71. National Institute of Environmental Health Sciences Auerbach SS. Stoner MA. Su S. Omiecinski CJ. Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3). 2005 Nov. Mol Pharmacol. 68(5):1239-53. National Institute of Environmental Health Sciences National Institute of General Medical Sciences Henderson RJ. Patton SM. Connor JR. Development of a fluorescent reporter to assess iron regulatory protein activity in living cells. 2005 Mar 22. Biochim Biophys Acta. 1743(1-2):162-8. National Institute of Environmental Health Sciences National Institute of Diabetes and Digestive and Kidney Diseases Kim DJ. Murray IA. Burns AM. Gonzalez FJ. Perdew GH. Peters JM. Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity. 2005 Mar 11. J Biol Chem. 280(10):9519-27. National Cancer Institute National Institute of Environmental Health Sciences Beischlag TV. Perdew GH. ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. 2005 Jun 3. J Biol Chem. 280(22):21607-11. National Institute of Environmental Health Sciences Reese BE. Davidson C. Billingsley ML. Yun J. Protein kinase C epsilon regulates tumor necrosis factor-alpha-induced stannin gene expression. 2005 Jul. J Pharmacol Exp Ther. 314(1):61-9. National Institute of Environmental Health Sciences Liang SH. Hassett C. Omiecinski CJ. Alternative promoters determine tissue-specific expression profiles of the human microsomal epoxide hydrolase gene (EPHX1). 2005 Jan. Mol Pharmacol. 67(1):220-30. National Institute of Environmental Health Sciences Janic B. Umstead TM. Phelps DS. Floros J. Modulatory effects of ozone on THP-1 cells in response to SP-A stimulation. 2005 Feb. Am J Physiol Lung Cell Mol Physiol. 288(2):L317-25. National Institute of Environmental Health Sciences Ramadoss P. Perdew GH. The transactivation domain of the Ah receptor is a key determinant of cellular localization and ligand-independent nucleocytoplasmic shuttling properties. 2005 Aug 23. Biochemistry. 44(33):11148-59. National Institute of Environmental Health Sciences Davidson CE. Reese BE. Billingsley ML. Yun JK. The protein stannin binds 14-3-3zeta and modulates mitogen-activated protein kinase signaling. 2005 Aug 18. Brain Res Mol Brain Res. 138(2):256-63. National Institute of Environmental Health Sciences Hollingshead BD. Petrulis JR. Perdew GH. The aryl hydrocarbon (Ah) receptor transcriptional regulator hepatitis B virus X-associated protein 2 antagonizes p23 binding to Ah receptor-Hsp90 complexes and is dispensable for receptor function. 2004 Oct 29. J Biol Chem. 279(44):45652-61. National Institute of Environmental Health Sciences Davidson CE. Reese BE. Billingsley ML. Yun JK. Stannin, a protein that localizes to the mitochondria and sensitizes NIH-3T3 cells to trimethyltin and dimethyltin toxicity. 2004 Oct. Mol Pharmacol. 66(4):855-63. National Institute of Environmental Health Sciences Huang W. Wang G. Phelps DS. Al-Mondhiry H. Floros J. Human SP-A genetic variants and bleomycin-induced cytokine production by THP-1 cells: effect of ozone-induced SP-A oxidation. 2004 Mar. Am J Physiol Lung Cell Mol Physiol. 286(3):L546-53. National Institute of Environmental Health Sciences National Heart, Lung, and Blood Institute Mijal RS. Thomson NM. Fleischer NL. Pauly GT. Moschel RC. Kanugula S. Fang Q. Pegg AE. Peterson LA. The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants. 2004 Mar. Chem Res Toxicol. 17(3):424-34. National Cancer Institute National Institute of Environmental Health Sciences Qian Z. Zhang J. Korn LR. Wei F. Chapman RS. Factor analysis of household factors: are they associated with respiratory conditions in Chinese children? 2004 Jun. Int J Epidemiol. 33(3):582-8. National Institute of Environmental Health Sciences Ding J. Umstead TM. Floros J. Phelps DS. Factors affecting SP-A-mediated phagocytosis in human monocytic cell lines. 2004 Jul. Respir Med. 98(7):637-50. National Institute of Environmental Health Sciences Storrs SI. Kiesecker JM. Survivorship patterns of larval amphibians exposed to low concentrations of atrazine. 2004 Jul. Environ Health Perspect. 112(10):1054-7. National Institute of Environmental Health Sciences Ramadoss P. Perdew GH. Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-p-dioxin as a probe to determine the relative ligand affinity of human versus mouse aryl hydrocarbon receptor in cultured cells. 2004 Jul. Mol Pharmacol. 66(1):129-36. National Institute of Environmental Health Sciences Valadez JG. Liu L. Loktionova NA. Pegg AE. Guengerich FP. Activation of bis-electrophiles to mutagenic conjugates by human O6-alkylguanine-DNA alkyltransferase. 2004 Jul. Chem Res Toxicol. 17(7):972-82. National Institute of Environmental Health Sciences National Cancer Institute Ramadoss P. Petrulis JR. Hollingshead BD. Kusnadi A. Perdew GH. Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes. 2004 Jan 27. Biochemistry. 43(3):700-9. National Institute of Environmental Health Sciences Rasimas JJ. Dalessio PA. Ropson IJ. Pegg AE. Fried MG. Active-site alkylation destabilizes human O6-alkylguanine DNA alkyltransferase. 2004 Jan. Protein Sci. 13(1):301-5. National Institute of Environmental Health Sciences National Institute of General Medical Sciences National Cancer Institute Liu L. Hachey DL. Valadez G. Williams KM. Guengerich FP. Loktionova NA. Kanugula S. Pegg AE. Characterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase. 2004 Feb 6. J Biol Chem. 279(6):4250-9. National Institute of Environmental Health Sciences National Cancer Institute Akgül B. Tu CP. Pentobarbital-mediated regulation of alternative polyadenylation in Drosophila glutathione S-transferase D21 mRNAs. 2004 Feb 6. J Biol Chem. 279(6):4027-33. National Institute of Environmental Health Sciences Liao D. Duan Y. Whitsel EA. Zheng ZJ. Heiss G. Chinchilli VM. Lin HM. Association of higher levels of ambient criteria pollutants with impaired cardiac autonomic control: a population-based study. 2004 Apr 15. Am J Epidemiol. 159(8):768-77. National Institute of Environmental Health Sciences Wang G. Bates-Kenney SR. Tao JQ. Phelps DS. Floros J. Differences in biochemical properties and in biological function between human SP-A1 and SP-A2 variants, and the impact of ozone-induced oxidation. 2004 Apr 13. Biochemistry. 43(14):4227-39. Public Health Service National Institute of Environmental Health Sciences Qian Z. Zhang JJ. Korn LR. Wei F. Chapman RS. Exposure-response relationships between lifetime exposure to residential coal smoke and respiratory symptoms and illnesses in Chinese children. 2004. J Expo Anal Environ Epidemiol. 14 Suppl 1:S78-84. National Institute of Environmental Health Sciences Sumanasekera WK. Tien ES. Davis JW. Turpey R. Perdew GH. Vanden Heuvel JP. Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARbeta activity. 2003 Sep 16. Biochemistry. 42(36):10726-35. National Institute of Environmental Health Sciences Rutkowski JM. Santiago LY. Ben-Jebria A. Ultman JS. Development of an assay for ozone-specific antioxidant capacity. 2003 Nov. Inhal Toxicol. 15(13):1369-85. National Institute of Environmental Health Sciences Vanden Heuvel JP. Kreder D. Belda B. Hannon DB. Nugent CA. Burns KA. Taylor MJ. Comprehensive analysis of gene expression in rat and human hepatoma cells exposed to the peroxisome proliferator WY14,643. 2003 May 1. Toxicol Appl Pharmacol. 188(3):185-98. National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Environmental Health Sciences Marden JH. Rogina B. Montooth KL. Helfand SL. Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies. 2003 Mar 18. Proc Natl Acad Sci U S A. 100(6):3369-73. National Institute on Aging National Institute of Environmental Health Sciences McElroy NR. Jurs PC. Morisseau C. Hammock BD. QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds. 2003 Mar 13. J Med Chem. 46(6):1066-80. National Institute of Environmental Health Sciences Petrulis JR. Kusnadi A. Ramadoss P. Hollingshead B. Perdew GH. The hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activity. 2003 Jan 24. J Biol Chem. 278(4):2677-85. National Institute of Environmental Health Sciences Janic B. Umstead TM. Phelps DS. Floros J. An in vitro cell model system for the study of the effects of ozone and other gaseous agents on phagocytic cells. 2003 Jan 15. J Immunol Methods. 272(1-2):125-34. National Institute of Environmental Health Sciences Rasimas JJ. Kanugula S. Dalessio PM. Ropson IJ. Fried MG. Pegg AE. Effects of zinc occupancy on human O6-alkylguanine-DNA alkyltransferase. 2003 Feb 4. Biochemistry. 42(4):980-90. National Institute of Environmental Health Sciences National Institute of General Medical Sciences National Cancer Institute Sumanasekera WK. Tien ES. Turpey R. Vanden Heuvel JP. Perdew GH. Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2. 2003 Feb 14. J Biol Chem. 278(7):4467-73. National Institute of Environmental Health Sciences Kimball SR. Horetsky RL. Ron D. Jefferson LS. Harding HP. Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes. 2003 Feb. Am J Physiol Cell Physiol. 284(2):C273-84. National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Environmental Health Sciences Pegg AE. Feith DJ. Fong LY. Coleman CS. O'Brien TG. Shantz LM. Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth. 2003 Apr. Biochem Soc Trans. 31(2):356-60. National Cancer Institute National Institute of Environmental Health Sciences Shappell NW. Carlino-MacDonald U. Amin S. Kumar S. Sikka HC. Comparative metabolism of chrysene and 5-methylchrysene by rat and rainbow trout liver microsomes. 2003 Apr. Toxicol Sci. 72(2):260-6. National Institute of Environmental Health Sciences Petrulis JR. Perdew GH. The role of chaperone proteins in the aryl hydrocarbon receptor core complex. 2002 Sep 20. Chem Biol Interact. 141(1-2):25-40. National Institute of Environmental Health Sciences Akgül B. Tu CP. Evidence for a stabilizer element in the untranslated regions of Drosophila glutathione S-transferase D1 mRNA. 2002 Sep 20. J Biol Chem. 277(38):34700-7. National Institute of Environmental Health Sciences Pizoli CE. Jinnah HA. Billingsley ML. Hess EJ. Abnormal cerebellar signaling induces dystonia in mice. 2002 Sep 1. J Neurosci. 22(17):7825-33. National Institute of Environmental Health Sciences National Institute of Neurological Disorders and Stroke Liu L. Pegg AE. Williams KM. Guengerich FP. Paradoxical enhancement of the toxicity of 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase. 2002 Oct 4. J Biol Chem. 277(40):37920-8. National Institute of Environmental Health Sciences National Cancer Institute Dull AB. Carlson DB. Petrulis JR. Perdew GH. Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2. 2002 Oct 15. Arch Biochem Biophys. 406(2):209-21. National Institute of Environmental Health Sciences Hu W. Feng Z. Eveleigh J. Iyer G. Pan J. Amin S. Chung FL. Tang MS. The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma. 2002 Nov. Carcinogenesis. 23(11):1781-9. National Institute of Environmental Health Sciences Kiesecker JM. Chivers DP. Anderson M. Blaustein AR. Effect of predator diet on life history shifts of red-legged frogs, Rana aurora. 2002 May. J Chem Ecol. 28(5):1007-15. National Institute of Environmental Health Sciences Kiesecker JM. Synergism between trematode infection and pesticide exposure: a link to amphibian limb deformities in nature? 2002 Jul 23. Proc Natl Acad Sci U S A. 99(15):9900-4. National Institute of Environmental Health Sciences Huang W. Wang G. Phelps DS. Al-Mondhiry H. Floros J. Combined SP-A-bleomycin effect on cytokines by THP-1 cells: impact of surfactant lipids on this effect. 2002 Jul. Am J Physiol Lung Cell Mol Physiol. 283(1):L94-L102. National Institute of Environmental Health Sciences National Heart, Lung, and Blood Institute Weber S. Dorman DC. Lash LH. Erikson K. Vrana KE. Aschner M. Effects of manganese (Mn) on the developing rat brain: oxidative-stress related endpoints. 2002 Jul. Neurotoxicology. 23(2):169-75. National Institute of Environmental Health Sciences Shellenberger K. Logan BE. Effect of molecular scale roughness of glass beads on colloidal and bacterial deposition. 2002 Jan 15. Environ Sci Technol. 36(2):184-9. National Institute of Environmental Health Sciences Wang G. Umstead TM. Phelps DS. Al-Mondhiry H. Floros J. The effect of ozone exposure on the ability of human surfactant protein a variants to stimulate cytokine production. 2002 Jan. Environ Health Perspect. 110(1):79-84. National Institute of Environmental Health Sciences National Heart, Lung, and Blood Institute Coleman CS. Pegg AE. Megosh LC. Guo Y. Sawicki JA. O'Brien TG. Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis. 2002 Feb. Carcinogenesis. 23(2):359-64. National Institute of Environmental Health Sciences National Institute of General Medical Sciences Reen RK. Cadwallader A. Perdew GH. The subdomains of the transactivation domain of the aryl hydrocarbon receptor (AhR) inhibit AhR and estrogen receptor transcriptional activity. 2002 Dec 1. Arch Biochem Biophys. 408(1):93-102. National Institute of Environmental Health Sciences Shantz LM. Guo Y. Sawicki JA. Pegg AE. O'Brien TG. Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation. 2002 Apr. Carcinogenesis. 23(4):657-64. National Cancer Institute National Institute of Environmental Health Sciences Carlson DB. Perdew GH. A dynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins. 2002. J Biochem Mol Toxicol. 16(6):317-25. National Institute of Environmental Health Sciences Swanson HI. Whitelaw ML. Petrulis JR. Perdew GH. Use of [125I]4'-iodoflavone as a tool to characterize ligand-dependent differences in Ah receptor behavior. 2002. J Biochem Mol Toxicol. 16(6):298-310. National Institute of Environmental Health Sciences Levine SL. Perdew GH. Okadaic acid increases ARNT homodimer transactivation potential. 2002. Cell Biol Toxicol. 18(2):109-20. National Institute of Environmental Health Sciences Petrulis JR. Perdew GH. Monitoring nuclear import with GFP-variant fusion proteins in digitonin-permeabilized cells. 2001 Oct. Biotechniques. 31(4):772-5. National Institute of Environmental Health Sciences Kumar MB. Ramadoss P. Reen RK. Vanden Heuvel JP. Perdew GH. The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity. 2001 Nov 9. J Biol Chem. 276(45):42302-10. National Institute of Environmental Health Sciences Floros J. Wang G. A point of view: quantitative and qualitative imbalance in disease pathogenesis; pulmonary surfactant protein A genetic variants as a model. 2001 May. Comp Biochem Physiol A Mol Integr Physiol. 129(1):295-303. National Institute of Environmental Health Sciences National Heart, Lung, and Blood Institute Levine SL. Perdew GH. Aryl hydrocarbon receptor (AhR)/AhR nuclear translocator (ARNT) activity is unaltered by phosphorylation of a periodicity/ARNT/single-minded (PAS)-region serine residue. 2001 Mar. Mol Pharmacol. 59(3):557-66. National Institute of Environmental Health Sciences Sorg BA. Tschirgi ML. Swindell S. Chen L. Fang J. Repeated formaldehyde effects in an animal model for multiple chemical sensitivity. 2001 Mar. Ann N Y Acad Sci. 933:57-67. National Institute on Drug Abuse National Institute of Environmental Health Sciences Bush ML. Zhang W. Ben-Jebria A. Ultman JS. Longitudinal distribution of ozone and chlorine in the human respiratory tract: simulation of nasal and oral breathing with the single-path diffusion model. 2001 Jun 15. Toxicol Appl Pharmacol. 173(3):137-45. National Institute of Environmental Health Sciences Cheng H. Tchaikovskaya T. Tu YS. Chapman J. Qian B. Ching WM. Tien M. Rowe JD. Patskovsky YV. Listowsky I. Tu CP. Rat glutathione S-transferase M4-4: an isoenzyme with unique structural features including a redox-reactive cysteine-115 residue that forms mixed disulphides with glutathione. 2001 Jun 1. Biochem J. 356(Pt 2):403-14. National Cancer Institute National Institute of Environmental Health Sciences Phelps DS. Surfactant regulation of host defense function in the lung: a question of balance. 2001 Jul-Aug. Pediatr Pathol Mol Med. 20(4):269-92. National Institute of Environmental Health Sciences National Heart, Lung, and Blood Institute King TS. Chinchilli VM. A generalized concordance correlation coefficient for continuous and categorical data. 2001 Jul 30. Stat Med. 20(14):2131-47. National Institute of Environmental Health Sciences Floros J. Human surfactant protein A (SP-A) variants: why so many, why such a complexity? 2001 Feb 24. Swiss Med Wkly. 131(7-8):87-90. National Heart, Lung, and Blood Institute National Institute of Environmental Health Sciences Senftleben U. Cao Y. Xiao G. Greten FR. Krähn G. Bonizzi G. Chen Y. Hu Y. Fong A. Sun SC. Karin M. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. 2001 Aug 24. Science. 293(5534):1495-9. National Institute of Allergy and Infectious Diseases National Institute of Environmental Health Sciences Santiago LY. Hann MC. Ben-Jebria A. Ultman JS. Ozone absorption in the human nose during unidirectional airflow. 2001 Aug. J Appl Physiol. 91(2):725-32. National Institute of Environmental Health Sciences Carlson DB. Williams DE. Spitsbergen JM. Ross PF. Bacon CW. Meredith FI. Riley RT. Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. 2001 Apr 1. Toxicol Appl Pharmacol. 172(1):29-36. National Institute of Environmental Health Sciences King TS. Chinchilli VM. Robust estimators of the concordance correlation coefficient. 2001. J Biopharm Stat. 11(3):83-105. National Institute of Environmental Health Sciences Smith LE. Denissenko MF. Bennett WP. Li H. Amin S. Tang M. Pfeifer GP. Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons. 2000 May 17. J Natl Cancer Inst. 92(10):803-11. National Institute of Environmental Health Sciences Wang G. Phelps DS. Umstead TM. Floros J. Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line. 2000 May. Am J Physiol Lung Cell Mol Physiol. 278(5):L946-54. National Heart, Lung, and Blood Institute National Institute of Environmental Health Sciences Liu H. Xu-Welliver M. Pegg AE. The role of human O(6)-alkylguanine-DNA alkyltransferase in promoting 1,2-dibromoethane-induced genotoxicity in Escherichia coli. 2000 Jul 20. Mutat Res. 452(1):1-10. National Cancer Institute National Institute of Environmental Health Sciences Meyer BK. Petrulis JR. Perdew GH. Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2. 2000 Jul. Cell Stress Chaperones. 5(3):243-54. National Institute of Environmental Health Sciences Philbert MA. Billingsley ML. Reuhl KR. Mechanisms of injury in the central nervous system. 2000 Jan-Feb. Toxicol Pathol. 28(1):43-53. National Institute of Environmental Health Sciences Pal A. Desai DH. Amin S. Srivastava SK. Hu X. Herzog C. Zimniak P. Singh SV. Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers. 2000 Dec 8. FEBS Lett. 486(2):163-6. National Cancer Institute National Institute of Environmental Health Sciences Petrulis JR. Hord NG. Perdew GH. Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2. 2000 Dec 1. J Biol Chem. 275(48):37448-53. National Institute of Environmental Health Sciences Levine SL. Petrulis JR. Dubil A. Perdew GH. A tetratricopeptide repeat half-site in the aryl hydrocarbon receptor is important for DNA binding and trans-activation potential. 2000 Dec. Mol Pharmacol. 58(6):1517-24. National Institute of Environmental Health Sciences Jefcoate CR. Liehr JG. Santen RJ. Sutter TR. Yager JD. Yue W. Santner SJ. Tekmal R. Demers L. Pauley R. Naftolin F. Mor G. Berstein L. Tissue-specific synthesis and oxidative metabolism of estrogens. 2000. J Natl Cancer Inst Monogr. 95-112. National Cancer Institute National Institute of Environmental Health Sciences Long WP. Perdew GH. Lack of an absolute requirement for the native aryl hydrocarbon receptor (AhR) and AhR nuclear translocator transactivation domains in protein kinase C-mediated modulation of the AhR pathway. 1999 Nov 15. Arch Biochem Biophys. 371(2):246-59. National Institute of Environmental Health Sciences Srivastava SK. Hu X. Xia H. Awasthi S. Amin S. Singh SV. Metabolic fate of glutathione conjugate of benzo[a]pyrene-(7R,8S)-diol (9S,10R)-epoxide in human liver. 1999 Nov 15. Arch Biochem Biophys. 371(2):340-4. National Cancer Institute National Institute of Environmental Health Sciences Meyer BK. Perdew GH. Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization. 1999 Jul 13. Biochemistry. 38(28):8907-17. National Institute of Environmental Health Sciences Vanden Heuvel JP. Peroxisome proliferator-activated receptors (PPARS) and carcinogenesis. 1999 Jan. Toxicol Sci. 47(1):1-8. National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Environmental Health Sciences Vanden Heuvel JP. Peroxisome proliferator-activated receptors: a critical link among fatty acids, gene expression and carcinogenesis. 1999 Feb. J Nutr. 129(2S Suppl):575S-580S. National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Environmental Health Sciences Nodelman V. Ultman JS. Longitudinal distribution of chlorine absorption in human airways: a comparison to ozone absorption. 1999 Dec. J Appl Physiol. 87(6):2073-80. National Institute of Environmental Health Sciences National Center for Research Resources Kumar MB. Tarpey RW. Perdew GH. Differential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifs. 1999 Aug 6. J Biol Chem. 274(32):22155-64. National Institute of Environmental Health Sciences Aschner M. Vrana KE. Zheng W. Manganese uptake and distribution in the central nervous system (CNS). 1999 Apr-Jun. Neurotoxicology. 20(2-3):173-80. National Institute of Environmental Health Sciences Long WP. Chen X. Perdew GH. Protein kinase C modulates aryl hydrocarbon receptor nuclear translocator protein-mediated transactivation potential in a dimer context. 1999 Apr 30. J Biol Chem. 274(18):12391-400. National Institute of Environmental Health Sciences Chae YH. Thomas T. Guengerich FP. Fu PP. El-Bayoumy K. Comparative metabolism of 1-, 2-, and 4-nitropyrene by human hepatic and pulmonary microsomes. 1999 Apr 1. Cancer Res. 59(7):1473-80. National Cancer Institute National Institute of Environmental Health Sciences Kumar MB. Perdew GH. Nuclear receptor coactivator SRC-1 interacts with the Q-rich subdomain of the AhR and modulates its transactivation potential. 1999. Gene Expr. 8(5-6):273-86. National Institute of Environmental Health Sciences Hu X. Pal A. Krzeminski J. Amin S. Awasthi YC. Zimniak P. Singh SV. Specificities of human glutathione S-transferase isozymes toward anti-diol epoxides of methylchrysenes. 1998 Sep. Carcinogenesis. 19(9):1685-9. National Cancer Institute National Institute of Environmental Health Sciences MacDougal CS. Rigas ML. Ben-Jebria A. Ultman JS. A respiratory ozone analyzer optimized for high resolution and swift dynamic response during exercise conditions. 1998 Mar-Apr. Arch Environ Health. 53(2):161-74. National Institute of Environmental Health Sciences Nunes MG. Desai D. Koehl W. Spratt TE. Guengerich FP. Amin S. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in human hepatic microsomes by ipomeanol analogs--an exploratory study. 1998 Jul 17. Cancer Lett. 129(2):131-8. National Cancer Institute National Institute of Environmental Health Sciences Fernandes A. Liu T. Amin S. Geacintov NE. Grollman AP. Moriya M. Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells. 1998 Jul 14. Biochemistry. 37(28):10164-72. National Cancer Institute National Institute of Environmental Health Sciences Dejneka NS. Polavarapu R. Deng X. Martin-DeLeon PA. Billingsley ML. Chromosomal localization and characterization of the stannin (Snn) gene. 1998 Jul. Mamm Genome. 9(7):556-64. National Institute of Environmental Health Sciences Meyer BK. Pray-Grant MG. Vanden Heuvel JP. Perdew GH. Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. 1998 Feb. Mol Cell Biol. 18(2):978-88. National Institute of Environmental Health Sciences Burkhart KK. Beard DC. Lehman RA. Billingsley ML. 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Protective effects of MK-801 on methamphetamine-induced depletion of dopaminergic and serotonergic terminals and striatal astrocytic response: an immunohistochemical study. 1995 Feb. Synapse. 19(2):97-104. National Institute on Drug Abuse National Institute of Environmental Health Sciences Lee HC. Tu CP. Drosophila glutathione S-transferase D27: functional analysis of two consecutive tyrosines near the N-terminus. 1995 Apr 6. Biochem Biophys Res Commun. 209(1):327-34. National Institute of Environmental Health Sciences National Institute of General Medical Sciences Garver TD. Oyler GA. Harris KA. Polavarapu R. Damuni Z. Lehman RA. Billingsley ML. Tau phosphorylation in brain slices: pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated protein kinase. 1995 Apr. Mol Pharmacol. 47(4):745-56. National Institute of Environmental Health Sciences Robertson JG. Adams GW. Medzihradszky KF. Burlingame AL. Villafranca JJ. Complete assignment of disulfide bonds in bovine dopamine beta-hydroxylase. 1994 Sep 27. Biochemistry. 33(38):11563-75. National Institute of General Medical Sciences National Institute of Environmental Health Sciences Orth AB. Rzhetskaya M. Cullen D. Tien M. Characterization of a cDNA encoding a manganese peroxidase from Phanerochaete chrysosporium: genomic organization of lignin and manganese peroxidase-encoding genes. 1994 Oct 11. Gene. 148(1):161-5. National Institute of Environmental Health Sciences Tang AH. Tu CP. Biochemical characterization of Drosophila glutathione S-transferases D1 and D21. 1994 Nov 11. J Biol Chem. 269(45):27876-84. National Center for Research Resources National Institute of Environmental Health Sciences National Institute of General Medical Sciences Yamazaki H. Mimura M. Oda Y. Gonzalez FJ. el-Bayoumy K. Chae YH. Guengerich FP. Shimada T. 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Coinduction of multiple hepatic cytochrome P-450 proteins and their mRNAs in rats treated with imidazole antimycotic agents. 1989 Mar. Mol Pharmacol. 35(3):279-85. National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Environmental Health Sciences Cai DY. Tien M. On the reactions of lignin peroxidase compound III (isozyme H8). 1989 Jul 14. Biochem Biophys Res Commun. 162(1):464-9. National Institute of Environmental Health Sciences Eskew ML. Zarkower A. Scheuchenzuber WJ. Burgess JR. Scholz RW. Hildenbrandt G. Reddy CC. Effects of inadequate vitamin E and/or selenium nutrition on the release of arachidonic acid metabolites in rat alveolar macrophages. 1989 Jul. Prostaglandins. 38(1):79-89. National Cancer Institute National Institute of Environmental Health Sciences National Heart, Lung, and Blood Institute Burgess JR. Chow NW. Reddy CC. Tu CP. 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Gene expression of rat glutathione S-transferases. Evidence for gene conversion in the evolution of the Yb multigene family. 1988 Aug 15. J Biol Chem. 263(23):11389-95. National Institute of Environmental Health Sciences Geddie JE. Amin S. Huie K. Hecht SS. Formation and tumorigenicity of benzo[b]fluoranthene metabolites in mouse epidermis. 1987 Nov. Carcinogenesis. 8(11):1579-84. National Institute of Environmental Health Sciences Chang M. Hong Y. Burgess JR. Tu CP. Reddy CC. Isozyme specificity of rat liver glutathione S-transferases in the formation of PGF2 alpha and PGE2 from PGH2. 1987 Dec. Arch Biochem Biophys. 259(2):548-57. National Institute of Environmental Health Sciences National Cancer Institute National Heart, Lung, and Blood Institute Chang M. Rao MK. Reddanna P. Li CH. Tu CP. Corey EJ. Reddy CC. Specificity of the glutathione S-transferases in the conversion of leukotriene A4 to leukotriene C4. 1987 Dec. Arch Biochem Biophys. 259(2):536-47. 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