Alistair J. Barber All publications ( 25 ) Xu Y. Ola MS. Berkich DA. Gardner TW. Barber AJ. Palmieri F. Hutson SM. LaNoue KF. Energy sources for glutamate neurotransmission in the retina: absence of the aspartate/glutamate carrier produces reliance on glycolysis in glia. 2007 Apr. J Neurochem. 101(1):120-31. National Eye Institute National Institute of Neurological Disorders and Stroke Antonetti DA. Barber AJ. Bronson SK. Freeman WM. Gardner TW. Jefferson LS. Kester M. Kimball SR. Krady JK. LaNoue KF. Norbury CC. Quinn PG. Sandirasegarane L. Simpson IA. JDRF Diabetic Retinopathy Center Group. Diabetic retinopathy: seeing beyond glucose-induced microvascular disease. 2006 Sep. Diabetes. 55(9):2401-11. National Eye Institute Santiago AR. Rosa SC. Santos PF. Cristóvão AJ. Barber AJ. Ambrósio AF. Elevated glucose changes the expression of ionotropic glutamate receptor subunits and impairs calcium homeostasis in retinal neural cells. 2006 Sep. Invest Ophthalmol Vis Sci. 47(9):4130-7. Gastinger MJ. Singh RS. Barber AJ. Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita-diabetic mouse retinas. 2006 Jul. Invest Ophthalmol Vis Sci. 47(7):3143-50. Barber AJ. Antonetti DA. Kern TS. Reiter CE. Soans RS. Krady JK. Levison SW. Gardner TW. Bronson SK. The Ins2Akita mouse as a model of early retinal complications in diabetes. 2005 Jun. Invest Ophthalmol Vis Sci. 46(6):2210-8. National Eye Institute Reiter CE. Sandirasegarane L. Wolpert EB. Klinger M. Simpson IA. Barber AJ. Antonetti DA. Kester M. Gardner TW. Characterization of insulin signaling in rat retina in vivo and ex vivo. 2003 Oct. Am J Physiol Endocrinol Metab. 285(4):E763-74. National Institute of General Medical Sciences Barber AJ. Antonetti DA. Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats. 2003 Dec. Invest Ophthalmol Vis Sci. 44(12):5410-6. National Eye Institute Barber AJ. A new view of diabetic retinopathy: a neurodegenerative disease of the eye. 2003 Apr. Prog Neuropsychopharmacol Biol Psychiatry. 27(2):283-90. Gardner TW. Antonetti DA. Barber AJ. LaNoue KF. Levison SW. Diabetic retinopathy: more than meets the eye. 2002 Dec. Surv Ophthalmol. 47 Suppl 2:S253-62. National Eye Institute Harhaj NS. Barber AJ. Antonetti DA. Platelet-derived growth factor mediates tight junction redistribution and increases permeability in MDCK cells. 2002 Dec. J Cell Physiol. 193(3):349-64. National Eye Institute Nakamura M. Barber AJ. Antonetti DA. LaNoue KF. Robinson KA. Buse MG. Gardner TW. Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons. 2001 Nov 23. J Biol Chem. 276(47):43748-55. National Institute of Diabetes and Digestive and Kidney Diseases National Eye Institute LaNoue KF. Berkich DA. Conway M. Barber AJ. Hu LY. Taylor C. Hutson S. Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina. 2001 Dec 1. J Neurosci Res. 66(5):914-22. National Institute of Neurological Disorders and Stroke Barber AJ. Nakamura M. Wolpert EB. Reiter CE. Seigel GM. Antonetti DA. Gardner TW. Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3. 2001 Aug 31. J Biol Chem. 276(35):32814-21. National Eye Institute Barber AJ. Antonetti DA. Gardner TW. Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. The Penn State Retina Research Group. 2000 Oct. Invest Ophthalmol Vis Sci. 41(11):3561-8. National Eye Institute Lieth E. Gardner TW. Barber AJ. Antonetti DA. Penn State Retina Research Group. Retinal neurodegeneration: early pathology in diabetes. 2000 Feb. Clin Experiment Ophthalmol. 28(1):3-8. Gardner TW. Antonetti DA. Barber AJ. LaNoue KF. Nakamura M. New insights into the pathophysiology of diabetic retinopathy: potential cell-specific therapeutic targets. 2000. Diabetes Technol Ther. 2(4):601-8. National Eye Institute Antonetti DA. Lieth E. Barber AJ. Gardner TW. Molecular mechanisms of vascular permeability in diabetic retinopathy. 1999 Dec. Semin Ophthalmol. 14(4):240-8. Antonetti DA. Barber AJ. Hollinger LA. Wolpert EB. Gardner TW. Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. A potential mechanism for vascular permeability in diabetic retinopathy and tumors. 1999 Aug 13. J Biol Chem. 274(33):23463-7. National Eye Institute Gardner TW. Antonetti DA. Barber AJ. Lieth E. Tarbell JA. The molecular structure and function of the inner blood-retinal barrier. Penn State Retina Research Group. 1999. Doc Ophthalmol. 97(3-4):229-37. Lieth E. Barber AJ. Xu B. Dice C. Ratz MJ. Tanase D. Strother JM. Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group. 1998 May. Diabetes. 47(5):815-20. Antonetti DA. Barber AJ. Khin S. Lieth E. Tarbell JM. Gardner TW. Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group. 1998 Dec. Diabetes. 47(12):1953-9. National Eye Institute Barber AJ. Lieth E. Khin SA. Antonetti DA. Buchanan AG. Gardner TW. Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin. 1998 Aug 15. J Clin Invest. 102(4):783-91. National Eye Institute Gardner TW. Lieth E. Khin SA. Barber AJ. Bonsall DJ. Lesher T. Rice K. Brennan WA. Astrocytes increase barrier properties and ZO-1 expression in retinal vascular endothelial cells. 1997 Oct. Invest Ophthalmol Vis Sci. 38(11):2423-7. National Eye Institute Barber AJ. Lieth E. Agrin accumulates in the brain microvascular basal lamina during development of the blood-brain barrier. 1997 Jan. Dev Dyn. 208(1):62-74. Gardner TW. Lesher T. Khin S. Vu C. Barber AJ. Brennan WA. Histamine reduces ZO-1 tight-junction protein expression in cultured retinal microvascular endothelial cells. 1996 Dec 15. Biochem J. 320 ( Pt 3):717-21. National Eye Institute