Arun Sharma
All publications ( 24 )
  • Cheung M. Sharma A. Madhunapantula SV. Robertson GP. Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development. 2008 May 1. Cancer Res. 68(9):3429-39.
  • Madhunapantula SV. Desai D. Sharma A. Huh SJ. Amin S. Robertson GP. PBISe, a novel selenium-containing drug for the treatment of malignant melanoma. 2008 May. Mol Cancer Ther. 7(5):1297-308.
  • Sharma AK. Gowdahalli K. Gimbor M. Amin S. Synthesis, microsome-mediated metabolism, and identification of major metabolites of environmental pollutant naphtho[8,1,2-ghi]chrysene. 2008 May. Chem Res Toxicol. 21(5):1154-62.
  • Salli U. Fox TE. Carkaci-Salli N. Sharma A. Robertson GP. Kester M. Vrana K. Propagation of undifferentiated human embryonic stem cells with nano-liposomal ceramide. 2008 Mar 10. Stem Cells Dev. .
  • Girroir EE. Hollingshead HE. Billin AN. Willson TM. Robertson GP. Sharma AK. Amin S. Gonzalez FJ. Peters JM. Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines. 2008 Jan 14. Toxicology. 243(1-2):236-43.
  • Borland MG. Foreman JE. Girroir EE. Zolfaghari R. Sharma AK. Amin SM. Gonzalez FJ. Ross AC. Peters JM. Ligand Activation of Peroxisome Proliferator-Activated Receptor-{beta}/{delta} (PPAR{beta}/{delta}) Inhibits Cell Proliferation in Human HaCaT Keratinocytes. 2008 Aug 13. Mol Pharmacol. .
  • Zheng Y. Sun D. Sharma AK. Chen G. Amin S. Lazarus P. Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. 2007 Oct. Drug Metab Dispos. 35(10):1942-8.
  • Sharma AK. Gowdahalli K. Krzeminski J. Amin S. Microwave-assisted Suzuki cross-coupling reaction, a key step in the synthesis of polycyclic aromatic hydrocarbons and their metabolites. 2007 Nov 9. J Org Chem. 72(23):8987-9.
  • Sun D. Sharma AK. Dellinger RW. Blevins-Primeau AS. Balliet RM. Chen G. Boyiri T. Amin S. Lazarus P. Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. 2007 Nov. Drug Metab Dispos. 35(11):2006-14.
  • Liang S. Sharma A. Peng HH. Robertson G. Dong C. Targeting mutant (V600E) B-Raf in melanoma interrupts immunoediting of leukocyte functions and melanoma extravasation. 2007 Jun 15. Cancer Res. 67(12):5814-20.
    National Cancer Institute
    National Center for Research Resources
  • Hollingshead HE. Killins RL. Borland MG. Girroir EE. Billin AN. Willson TM. Sharma AK. Amin S. Gonzalez FJ. Peters JM. Peroxisome proliferator-activated receptor-{beta}/{delta} (PPAR{beta}/{delta}) ligands do not potentiate growth of human cancer cell lines. 2007 Aug 11. Carcinogenesis. .
  • Madhunapantula SV. Sharma A. Robertson GP. PRAS40 deregulates apoptosis in malignant melanoma. 2007 Apr 15. Cancer Res. 67(8):3626-36.
  • Sharma A. Tran MA. Liang S. Sharma AK. Amin S. Smith CD. Dong C. Robertson GP. Targeting Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in the Mutant (V600E) B-Raf Signaling Cascade Effectively Inhibits Melanoma Lung Metastases. 2006 Aug 15. Cancer Res. 66(16):8200-9.
  • Sharma AK. Amin S. Synthesis and identification of major metabolites of environmental pollutant dibenzo[c,mno]chrysene. 2005 Sep. Chem Res Toxicol. 18(9):1438-43.
    National Cancer Institute
  • Stover TC. Sharma A. Robertson GP. Kester M. Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma. 2005 May 1. Clin Cancer Res. 11(9):3465-74.
    National Heart, Lung, and Blood Institute
  • Sharma A. Trivedi NR. Zimmerman MA. Tuveson DA. Smith CD. Robertson GP. Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors. 2005 Mar 15. Cancer Res. 65(6):2412-21.
  • Sharma AK. Lin JM. Desai D. Amin S. Convenient syntheses of dibenzo[c,p]chrysene and its possible proximate and ultimate carcinogens: in vitro metabolism and DNA adduction studies. 2005 Jun 24. J Org Chem. 70(13):4962-70.
    National Cancer Institute
  • Stahl JM. Sharma A. Cheung M. Zimmerman M. Cheng JQ. Bosenberg MW. Kester M. Sandirasegarane L. Robertson GP. Deregulated Akt3 activity promotes development of malignant melanoma. 2004 Oct 1. Cancer Res. 64(19):7002-10.
  • Sharma AK. Kumar S. Amin S. A Highly Abbreviated Synthesis of Dibenzo[def,p]chrysene and Its 12-Methoxy Derivative, a Key Precursor for the Synthesis of the Proximate and Ultimate Carcinogens of Dibenzo[def,p]chrysene. 2004 May 28. J Org Chem. 69(11):3979-82.
    National Cancer Institute
  • El-Bayoumy K. Sharma AK. Lin JM. Krzeminski J. Boyiri T. King LC. Lambert G. Padgett W. Nesnow S. Amin S. Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene. 2004 Dec. Chem Res Toxicol. 17(12):1591-9.
    National Cancer Institute
  • Sun YW. Guengerich FP. Sharma AK. Boyiri T. Amin S. el-Bayoumy K. Human cytochromes P450 1A1 and 1B1 catalyze ring oxidation but not nitroreduction of environmental pollutant mononitropyrene isomers in primary cultures of human breast cells and cultured MCF-10A and MCF-7 cell lines. 2004 Aug. Chem Res Toxicol. 17(8):1077-85.
    National Cancer Institute
  • Stahl JM. Cheung M. Sharma A. Trivedi NR. Shanmugam S. Robertson GP. Loss of PTEN promotes tumor development in malignant melanoma. 2003 Jun 1. Cancer Res. 63(11):2881-90.
  • Desai D. Sharma AK. Lin JM. Krzeminski J. Pimentel M. El-Bayoumy K. Nesnow S. Amin S. Synthesis, in vitro metabolism, cell transformation, mutagenicity, and DNA adduction of dibenzo[c,mno]chrysene. 2002 Jul. Chem Res Toxicol. 15(7):964-71.
    National Cancer Institute
  • El-Bayoumy K. Desai D. Boyiri T. Rosa J. Krzeminski J. Sharma AK. Pittman B. Amin S. Comparative tumorigenicity of the environmental pollutant 6-nitrochrysene and its metabolites in the rat mammary gland. 2002 Jul. Chem Res Toxicol. 15(7):972-8.
    National Cancer Institute