Charles D. Smith All publications ( 26 ) Tran MA. Smith CD. Kester M. Robertson GP. Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development. 2008 Jun 1. Clin Cancer Res. 14(11):3571-81. Seaton KE. Smith CD. N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef. 2008 Jan. J Gen Virol. 89(Pt 1):288-96. Maines LW. Fitzpatrick LR. French KJ. Zhuang Y. Xia Z. Keller SN. Upson JJ. Smith CD. Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase. 2008 Apr. Dig Dis Sci. 53(4):997-1012. Plastaras JP. Kim SH. Liu YY. Dicker DT. Dorsey JF. McDonough J. Cerniglia G. Rajendran RR. Gupta A. Rustgi AK. Diehl JA. Smith CD. Flaherty KT. El-Deiry WS. Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation. 2007 Oct 1. Cancer Res. 67(19):9443-54. Draper JM. Xia Z. Smith CD. Cellular palmitoylation and trafficking of lipidated peptides. 2007 Aug. J Lipid Res. 48(8):1873-84. Ducker CE. Draper JM. Xia Z. Smith CD. In vitro and cellular assays for palmitoyl acyltransferases using fluorescent lipidated peptides. 2006 Oct. Methods. 40(2):166-70. Maines LW. French KJ. Wolpert EB. Antonetti DA. Smith CD. Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. 2006 Nov. Invest Ophthalmol Vis Sci. 47(11):5022-31. National Eye Institute Sharma A. Tran MA. Liang S. Sharma AK. Amin S. Smith CD. Dong C. Robertson GP. Targeting Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in the Mutant (V600E) B-Raf Signaling Cascade Effectively Inhibits Melanoma Lung Metastases. 2006 Aug 15. Cancer Res. 66(16):8200-9. French KJ. Upson JJ. Keller SN. Zhuang Y. Yun JK. Smith CD. Antitumor activity of sphingosine kinase inhibitors. 2006 Aug. J Pharmacol Exp Ther. 318(2):596-603. National Cancer Institute Maines LW. Antonetti DA. Wolpert EB. Smith CD. Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells. 2005 Oct. Neuropharmacology. 49(5):610-7. National Eye Institute Sharma A. Trivedi NR. Zimmerman MA. Tuveson DA. Smith CD. Robertson GP. Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors. 2005 Mar 15. Cancer Res. 65(6):2412-21. Ducker CE. Upson JJ. French KJ. Smith CD. Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 Aug. Mol Cancer Res. 3(8):463-76. National Cancer Institute Lee BD. Li Z. French KJ. Zhuang Y. Xia Z. Smith CD. Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. 2004 Mar 11. J Med Chem. 47(6):1413-22. National Cancer Institute Ducker CE. Stettler EM. French KJ. Upson JJ. Smith CD. Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase. 2004 Dec 9. Oncogene. 23(57):9230-7. National Cancer Institute French KJ. Zhuang Y. Schrecengost RS. Copper JE. Xia Z. Smith CD. Cyclohexyl-octahydro-pyrrolo[1,2-a]pyrazine-based inhibitors of human N-myristoyltransferase-1. 2004 Apr. J Pharmacol Exp Ther. 309(1):340-7. National Cancer Institute French KJ. Schrecengost RS. Lee BD. Zhuang Y. Smith SN. Eberly JL. Yun JK. Smith CD. Discovery and evaluation of inhibitors of human sphingosine kinase. 2003 Sep 15. Cancer Res. 63(18):5962-9. National Cancer Institute Varner AS. Ducker CE. Xia Z. Zhuang Y. De Vos ML. Smith CD. Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs. 2003 Jul 1. Biochem J. 373(Pt 1):91-9. National Cancer Institute Lee BD. French KJ. Zhuang Y. Smith CD. Development of a syngeneic in vivo tumor model and its use in evaluating a novel P-glycoprotein modulator, PGP-4008. 2003. Oncol Res. 14(1):49-60. National Cancer Institute Varner AS. De Vos ML. Creaser SP. Peterson BR. Smith CD. A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity. 2002 Sep 1. Anal Biochem. 308(1):160-7. National Cancer Institute De Vos ML. Lawrence DS. Smith CD. Cellular pharmacology of cerulenin analogs that inhibit protein palmitoylation. 2001 Oct 15. Biochem Pharmacol. 62(8):985-95. National Cancer Institute Xia Z. Smith CD. Total synthesis of dendroamide A, a novel cyclic peptide that reverses multiple drug resistance. 2001 May 18. J Org Chem. 66(10):3459-66. National Cancer Institute Xia Z. Smith CD. Efficient synthesis of a fluorescent farnesylated Ras peptide. 2001 Jul 27. J Org Chem. 66(15):5241-4. National Cancer Institute Lawrence DS. Copper JE. Smith CD. Structure-activity studies of substituted quinoxalinones as multiple-drug-resistance antagonists. 2001 Feb 15. J Med Chem. 44(4):594-601. National Cancer Institute Smith CD. Myers CB. Zilfou JT. Smith SN. Lawrence DS. Indoloquinoxaline compounds that selectively antagonize P-glycoprotein. 2000. Oncol Res. 12(5):219-29. National Cancer Institute Lawrence DS. Zilfou JT. Smith CD. Structure-activity studies of cerulenin analogues as protein palmitoylation inhibitors. 1999 Dec 2. J Med Chem. 42(24):4932-41. National Cancer Institute Post RM. Ballenger JC. Uhde TW. Smith C. Rubinow DR. Bunney WE. Effect of carbamazepine on cyclic nucleotides in CSF of patients with affective illness. 1982 Sep. Biol Psychiatry. 17(9):1037-45.