Catherine Coleman
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Academic title Assistant Professor of Cellular and Molecular Physiology
College College of Medicine
Campuses Penn State Milton S. Hershey Medical Center
Department Cellular and Molecular Physiology
Graduate programs
Email Phone
  ccoleman@psu.edu
  717 531 0021
 
Educational background
  Ph. D., University of Aberdeen, 1991
Postdoctoral Training, Pennsylvania State University College of Medicine, 1991-1994
Areas of expertise
 
AcetyltransferasesGenetic Predisposition to Disease
Skin NeoplasmsSpermine
Ornithine DecarboxylasePoint Mutation
MutationAnticarcinogenic Agents
Enzyme InhibitorsCell Transformation, Neoplastic
Transcription FactorsCysteine Endopeptidases
Glutamic AcidMultienzyme Complexes
OrnithineGene Expression Regulation, Enzymologic
PolyaminesSpermidine
Biogenic PolyaminesMice, Transgenic
NeoplasmsMammals
PutrescineSpermine Synthase
Genes, MHC Class IImmunoglobulin Heavy Chains
RNA-Binding ProteinsUbiquitin-Conjugating Enzymes
Viral Proteins
Publication author name
  Coleman C
Coleman CS
Select publications
  Shantz LM. Coleman CS. Pegg AE. Expression of an ornithine decarboxylase dominant-negative mutant reverses eukaryotic initiation factor 4E-induced cell transformation. 1996 Nov 15. Cancer Res. 56(22):5136-40.
National Cancer Institute
Coleman CS. Pegg AE. Proteasomal degradation of spermidine/spermine N1-acetyltransferase requires the carboxyl-terminal glutamic acid residues. 1997 May 2. J Biol Chem. 272(18):12164-9.
National Institute of General Medical Sciences
Coleman CS. Pegg AE. Assay of mammalian ornithine decarboxylase activity using [14C]ornithine. 1998. Methods Mol Biol. 79:41-4.
McCloskey DE. Coleman CS. Pegg AE. Properties and regulation of human spermidine/spermine N1-acetyltransferase stably expressed in Chinese hamster ovary cells. 1999 Mar 5. J Biol Chem. 274(10):6175-82.
National Institute of General Medical Sciences
Coleman CS. Pegg AE. Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradation. 2001 Aug 15. Biochem J. 358(Pt 1):137-45.
National Institute of General Medical Sciences

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