Hui-Ling Chiang
All publications ( 24 )
  • Brown CR. Wolfe AB. Cui D. Chiang HL. The vacuolar import and degradation pathway merges with the endocytic pathway to deliver fructose-1,6-bisphosphatase to the vacuole for degradation. 2008 Jul 25. J Biol Chem. .
  • Liu J. Brown CR. Chiang HL. Degradation of the gluconeogenic enzyme fructose-1, 6-bisphosphatase is dependent on the vacuolar ATPase. 2005 Oct-Dec. Autophagy. 1(3):146-56.
    National Institute of General Medical Sciences
  • Hung GC. Brown CR. Wolfe AB. Liu J. Chiang HL. Degradation of the gluconeogenic enzymes fructose-1,6-bisphosphatase and malate dehydrogenase is mediated by distinct proteolytic pathways and signaling events. 2004 Nov 19. J Biol Chem. 279(47):49138-50.
    National Institute of General Medical Sciences
  • Cui DY. Brown CR. Chiang HL. The type 1 phosphatase Reg1p-Glc7p is required for the glucose-induced degradation of fructose-1,6-bisphosphatase in the vacuole. 2004 Mar 12. J Biol Chem. 279(11):9713-24.
    National Institute of General Medical Sciences
  • Brown CR. Liu J. Hung GC. Carter D. Cui D. Chiang HL. The Vid vesicle to vacuole trafficking event requires components of the SNARE membrane fusion machinery. 2003 Jul 11. J Biol Chem. 278(28):25688-99.
  • Brown CR. McCann JA. Hung GG. Elco CP. Chiang HL. Vid22p, a novel plasma membrane protein, is required for the fructose-1,6-bisphosphatase degradation pathway. 2002 Feb 1. J Cell Sci. 115(Pt 3):655-66.
    National Institute of General Medical Sciences
  • Shieh HL. Chen Y. Brown CR. Chiang HL. Biochemical analysis of fructose-1,6-bisphosphatase import into vacuole import and degradation vesicles reveals a role for UBC1 in vesicle biogenesis. 2001 Mar 30. J Biol Chem. 276(13):10398-406.
    National Institute of General Medical Sciences
  • Brown CR. Cui DY. Hung GG. Chiang HL. Cyclophilin A mediates Vid22p function in the import of fructose-1,6-bisphosphatase into Vid vesicles. 2001 Dec 21. J Biol Chem. 276(51):48017-26.
    National Institute of General Medical Sciences
  • Brown CR. McCann JA. Chiang HL. The heat shock protein Ssa2p is required for import of fructose-1, 6-bisphosphatase into Vid vesicles. 2000 Jul 10. J Cell Biol. 150(1):65-76.
    National Institute of General Medical Sciences
  • Chiang MC. Chiang HL. Vid24p, a novel protein localized to the fructose-1, 6-bisphosphatase-containing vesicles, regulates targeting of fructose-1,6-bisphosphatase from the vesicles to the vacuole for degradation. 1998 Mar 23. J Cell Biol. 140(6):1347-56.
    National Institute of General Medical Sciences
  • Shieh HL. Chiang HL. In vitro reconstitution of glucose-induced targeting of fructose-1, 6-bisphosphatase into the vacuole in semi-intact yeast cells. 1998 Feb 6. J Biol Chem. 273(6):3381-7.
    National Institute of General Medical Sciences
  • Huang PH. Chiang HL. Identification of novel vesicles in the cytosol to vacuole protein degradation pathway. 1997 Feb 24. J Cell Biol. 136(4):803-10.
  • Hoffman M. Chiang HL. Isolation of degradation-deficient mutants defective in the targeting of fructose-1,6-bisphosphatase into the vacuole for degradation in Saccharomyces cerevisiae. 1996 Aug. Genetics. 143(4):1555-66.
  • Chiang HL. Schekman R. Hamamoto S. Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation. 1996 Apr 26. J Biol Chem. 271(17):9934-41.
    National Institute of General Medical Sciences
  • Terlecky SR. Chiang HL. Olson TS. Dice JF. Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein. 1992 May 5. J Biol Chem. 267(13):9202-9.
    National Institute on Aging
    National Institute of Diabetes and Digestive and Kidney Diseases
  • Chiang HL. Schekman R. Regulated import and degradation of a cytosolic protein in the yeast vacuole. 1991 Mar 28. Nature. 350(6316):313-8.
  • Wing SS. Chiang HL. Goldberg AL. Dice JF. Proteins containing peptide sequences related to Lys-Phe-Glu-Arg-Gln are selectively depleted in liver and heart, but not skeletal muscle, of fasted rats. 1991 Apr 1. Biochem J. 275 ( Pt 1):165-9.
  • Dice JF. Terlecky SR. Chiang HL. Olson TS. Isenman LD. Short-Russell SR. Freundlieb S. Terlecky LJ. A selective pathway for degradation of cytosolic proteins by lysosomes. 1990 Dec. Semin Cell Biol. 1(6):449-55.
    National Institute on Aging
    National Institute of Diabetes and Digestive and Kidney Diseases
  • Chiang HL. Terlecky SR. Plant CP. Dice JF. A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. 1989 Oct 20. Science. 246(4928):382-5.
    National Institute on Aging
    National Institute of Diabetes and Digestive and Kidney Diseases
  • Dice JF. Chiang HL. Peptide signals for protein degradation within lysosomes. 1989. Biochem Soc Symp. 55:45-55.
  • Dice JF. Chiang HL. Lysosomal degradation of microinjected proteins. 1989. Revis Biol Celular. 20:13-33.
  • Chiang HL. Dice JF. Peptide sequences that target proteins for enhanced degradation during serum withdrawal. 1988 May 15. J Biol Chem. 263(14):6797-805.
  • Dice JF. Backer JM. Chiang HL. Goff SA. Lysosomal degradation of microinjected proteins. 1987 Oct. Biochem Soc Trans. 15(5):824-6.
    National Institute on Aging
    National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases
  • Dice JF. Chiang HL. Spencer EP. Backer JM. Regulation of catabolism of microinjected ribonuclease A. Identification of residues 7-11 as the essential pentapeptide. 1986 May 25. J Biol Chem. 261(15):6853-9.
    National Institute on Aging