Jason K. Kim All publications ( 26 ) Cho YR. Kim HJ. Park SY. Ko HJ. Hong EG. Higashimori T. Zhang Z. Jung DY. Ola MS. Lanoue KF. Leiter EH. Kim JK. Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes. 2007 Jul. Am J Physiol Endocrinol Metab. 293(1):E327-36. National Institute of Diabetes and Digestive and Kidney Diseases Hong EG. Jung DY. Ko HJ. Zhang Z. Ma Z. Jun JY. Kim JH. Sumner AD. Vary TC. Gardner TW. Bronson SK. Kim JK. Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling. 2007 Dec. Am J Physiol Endocrinol Metab. 293(6):E1687-96. Delibegovic M. Bence KK. Mody N. Hong EG. Ko HJ. Kim JK. Kahn BB. Neel BG. Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B). 2007 Aug 27. Mol Cell Biol. . Park SY. Cho YR. Kim HJ. Hong EG. Higashimori T. Lee SJ. Goldberg IJ. Shulman GI. Najjar SM. Kim JK. Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1. 2006 Sep. Am J Physiol Endocrinol Metab. 291(3):E517-24. National Institute of Diabetes and Digestive and Kidney Diseases Dubois MJ. Bergeron S. Kim HJ. Dombrowski L. Perreault M. Fournès B. Faure R. Olivier M. Beauchemin N. Shulman GI. Siminovitch KA. Kim JK. Marette A. The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis. 2006 May. Nat Med. 12(5):549-56. National Institute of Diabetes and Digestive and Kidney Diseases Matsui T. Nagoshi T. Hong EG. Luptak I. Hartil K. Li L. Gorovits N. Charron MJ. Kim JK. Tian R. Rosenzweig A. Effects of chronic Akt activation on glucose uptake in the heart. 2006 May. Am J Physiol Endocrinol Metab. 290(5):E789-97. National Institute of Diabetes and Digestive and Kidney Diseases National Heart, Lung, and Blood Institute Cao H. Maeda K. Gorgun CZ. Kim HJ. Park SY. Shulman GI. Kim JK. Hotamisligil GS. Regulation of metabolic responses by adipocyte/macrophage Fatty Acid-binding proteins in leptin-deficient mice. 2006 Jul. Diabetes. 55(7):1915-22. National Institute of Diabetes and Digestive and Kidney Diseases Wu JJ. Roth RJ. Anderson EJ. Hong EG. Lee MK. Choi CS. Neufer PD. Shulman GI. Kim JK. Bennett AM. Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity. 2006 Jul. Cell Metab. 4(1):61-73. National Institute of Diabetes and Digestive and Kidney Diseases National Cancer Institute Kim JK. Fat uses a TOLL-road to connect inflammation and diabetes. 2006 Dec. Cell Metab. 4(6):417-9. Park SY. Cho YR. Finck BN. Kim HJ. Higashimori T. Hong EG. Lee MK. Danton C. Deshmukh S. Cline GW. Wu JJ. Bennett AM. Rothermel B. Kalinowski A. Russell KS. Kim YB. Kelly DP. Kim JK. Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. 2005 Sep. Diabetes. 54(9):2514-24. National Heart, Lung, and Blood Institute National Institute of Diabetes and Digestive and Kidney Diseases Kim JK. Kim HJ. Park SY. Cederberg A. Westergren R. Nilsson D. Higashimori T. Cho YR. Liu ZX. Dong J. Cline GW. Enerback S. Shulman GI. Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance. 2005 Jun. Diabetes. 54(6):1657-63. National Institute of Diabetes and Digestive and Kidney Diseases Capozza F. Combs TP. Cohen AW. Cho YR. Park SY. Schubert W. Williams TM. Brasaemle DL. Jelicks LA. Scherer PE. Kim JK. Lisanti MP. Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle. 2005 Jun. Am J Physiol Cell Physiol. 288(6):C1317-31. National Institute of Diabetes and Digestive and Kidney Diseases National Institute of General Medical Sciences Park SY. Kim HJ. Wang S. Higashimori T. Dong J. Kim YJ. Cline G. Li H. Prentki M. Shulman GI. Mitchell GA. Kim JK. Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart. 2005 Jul. Am J Physiol Endocrinol Metab. 289(1):E30-9. National Institute of Diabetes and Digestive and Kidney Diseases Park SY. Cho YR. Kim HJ. Higashimori T. Danton C. Lee MK. Dey A. Rothermel B. Kim YB. Kalinowski A. Russell KS. Kim JK. Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice. 2005 Dec. Diabetes. 54(12):3530-40. National Institute of Diabetes and Digestive and Kidney Diseases Furukawa N. Ongusaha P. Jahng WJ. Araki K. Choi CS. Kim HJ. Lee YH. Kaibuchi K. Kahn BB. Masuzaki H. Kim JK. Lee SW. Kim YB. Role of Rho-kinase in regulation of insulin action and glucose homeostasis. 2005 Aug. Cell Metab. 2(2):119-29. National Cancer Institute National Institute of Diabetes and Digestive and Kidney Diseases Public Health Service Spurlin BA. Park SY. Nevins AK. Kim JK. Thurmond DC. Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle. 2004 Sep. Diabetes. 53(9):2223-31. National Institute of Diabetes and Digestive and Kidney Diseases Kim JK. Fillmore JJ. Sunshine MJ. Albrecht B. Higashimori T. Kim DW. Liu ZX. Soos TJ. Cline GW. O'Brien WR. Littman DR. Shulman GI. PKC-theta knockout mice are protected from fat-induced insulin resistance. 2004 Sep. J Clin Invest. 114(6):823-7. National Institute of Diabetes and Digestive and Kidney Diseases Erol E. Cline GW. Kim JK. Taegtmeyer H. Binas B. Nonacute effects of H-FABP deficiency on skeletal muscle glucose uptake in vitro. 2004 Nov. Am J Physiol Endocrinol Metab. 287(5):E977-82. National Institute of Diabetes and Digestive and Kidney Diseases Kim JK. Gimeno RE. Higashimori T. Kim HJ. Choi H. Punreddy S. Mozell RL. Tan G. Stricker-Krongrad A. Hirsch DJ. Fillmore JJ. Liu ZX. Dong J. Cline G. Stahl A. Lodish HF. Shulman GI. Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. 2004 Mar. J Clin Invest. 113(5):756-63. National Heart, Lung, and Blood Institute National Institute of Diabetes and Digestive and Kidney Diseases Zabolotny JM. Haj FG. Kim YB. Kim HJ. Shulman GI. Kim JK. Neel BG. Kahn BB. Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action. 2004 Jun 4. J Biol Chem. 279(23):24844-51. National Institute of Diabetes and Digestive and Kidney Diseases National Cancer Institute Augustus A. Yagyu H. Haemmerle G. Bensadoun A. Vikramadithyan RK. Park SY. Kim JK. Zechner R. Goldberg IJ. Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression. 2004 Jun 11. J Biol Chem. 279(24):25050-7. National Heart, Lung, and Blood Institute National Institute of Diabetes and Digestive and Kidney Diseases Tsai YS. Kim HJ. Takahashi N. Kim HS. Hagaman JR. Kim JK. Maeda N. Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma. 2004 Jul. J Clin Invest. 114(2):240-9. National Institute of Diabetes and Digestive and Kidney Diseases National Heart, Lung, and Blood Institute Kim HJ. Higashimori T. Park SY. Choi H. Dong J. Kim YJ. Noh HL. Cho YR. Cline G. Kim YB. Kim JK. Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo. 2004 Apr. Diabetes. 53(4):1060-7. Rangwala SM. Rhoades B. Shapiro JS. Rich AS. Kim JK. Shulman GI. Kaestner KH. Lazar MA. Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity. 2003 Oct. Dev Cell. 5(4):657-63. National Institute of Diabetes and Digestive and Kidney Diseases Kim JK. Fillmore JJ. Gavrilova O. Chao L. Higashimori T. Choi H. Kim HJ. Yu C. Chen Y. Qu X. Haluzik M. Reitman ML. Shulman GI. Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice. 2003 Jun. Diabetes. 52(6):1311-8. National Institute of Diabetes and Digestive and Kidney Diseases Spurlin BA. Thomas RM. Nevins AK. Kim HJ. Kim YJ. Noh HL. Shulman GI. Kim JK. Thurmond DC. Insulin resistance in tetracycline-repressible Munc18c transgenic mice. 2003 Aug. Diabetes. 52(8):1910-7. National Institute of Diabetes and Digestive and Kidney Diseases