Mark Kester All publications ( 28 ) Matters GL. Harms JF. McGovern CO. Jayakumar C. Crepin K. Smith ZP. Nelson MC. Stock H. Fenn CW. Kaiser J. Kester M. Smith JP. Growth of Human Pancreatic Cancer Is Inhibited by Down-Regulation of Gastrin Gene Expression. 2009 May 22. Pancreas. . Heakal Y. Kester M. Nanoliposomal short-chain ceramide inhibits agonist-dependent translocation of neurotensin receptor 1 to structured membrane microdomains in breast cancer cells. 2009 May. Mol Cancer Res. 7(5):724-34. Ganapathi SB. Kester M. Elmslie KS. State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy. 2009 Apr. Am J Physiol Cell Physiol. 296(4):C701-10. Tran MA. Gowda R. Sharma A. Park EJ. Adair J. Kester M. Smith NB. Robertson GP. Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development. 2008 Sep 15. Cancer Res. 68(18):7638-49. Houck KL. Fox TE. Sandirasegarane L. Kester M. Ether-linked diglycerides inhibit vascular smooth muscle cell growth via decreased MAPK and PI3K/Akt signaling. 2008 Oct. Am J Physiol Heart Circ Physiol. 295(4):H1657-68. Salli U. Fox TE. Carkaci-Salli N. Sharma A. Robertson GP. Kester M. Vrana K. Propagation of undifferentiated human embryonic stem cells with nano-liposomal ceramide. 2008 Mar 10. Stem Cells Dev. . Tran MA. Smith CD. Kester M. Robertson GP. Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development. 2008 Jun 1. Clin Cancer Res. 14(11):3571-81. Sun Y. Fox T. Adhikary G. Kester M. Pearlman E. Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide. 2008 Jun. J Leukoc Biol. 83(6):1512-21. Pearlman E. Johnson A. Adhikary G. Sun Y. Chinnery HR. Fox T. Kester M. McMenamin PG. Toll-like receptors at the ocular surface. 2008 Jul. Ocul Surf. 6(3):108-16. Stover TC. Kim YS. Lowe TL. Kester M. Thermoresponsive and biodegradable linear-dendritic nanoparticles for targeted and sustained release of a pro-apoptotic drug. 2008 Jan. Biomaterials. 29(3):359-69. Fox TE. Houck KL. O'Neill SM. Nagarajan M. Stover TC. Pomianowski PT. Unal O. Yun JK. Naides SJ. Kester M. Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains. 2007 Apr 27. J Biol Chem. 282(17):12450-7. National Heart, Lung, and Blood Institute Antonetti DA. Barber AJ. Bronson SK. Freeman WM. Gardner TW. Jefferson LS. Kester M. Kimball SR. Krady JK. LaNoue KF. Norbury CC. Quinn PG. Sandirasegarane L. Simpson IA. JDRF Diabetic Retinopathy Center Group. Diabetic retinopathy: seeing beyond glucose-induced microvascular disease. 2006 Sep. Diabetes. 55(9):2401-11. National Eye Institute Fox TE. Finnegan CM. Blumenthal R. Kester M. The clinical potential of sphingolipid-based therapeutics. 2006 May. Cell Mol Life Sci. 63(9):1017-23. Basile M. Lin R. Kabbani N. Karpa K. Kilimann M. Simpson I. Kester M. Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling. 2006 Feb 1. Arch Biochem Biophys. 446(1):60-8. Fox TE. Han X. Kelly S. Merrill AH. Martin RE. Anderson RE. Gardner TW. Kester M. Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy. 2006 Dec. Diabetes. 55(12):3573-80. National Institute on Aging National Eye Institute National Center for Research Resources Stover TC. Sharma A. Robertson GP. Kester M. Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma. 2005 May 1. Clin Cancer Res. 11(9):3465-74. National Heart, Lung, and Blood Institute Stahl JM. Sharma A. Cheung M. Zimmerman M. Cheng JQ. Bosenberg MW. Kester M. Sandirasegarane L. Robertson GP. Deregulated Akt3 activity promotes development of malignant melanoma. 2004 Oct 1. Cancer Res. 64(19):7002-10. Reiter CE. Sandirasegarane L. Wolpert EB. Klinger M. Simpson IA. Barber AJ. Antonetti DA. Kester M. Gardner TW. Characterization of insulin signaling in rat retina in vivo and ex vivo. 2003 Oct. Am J Physiol Endocrinol Metab. 285(4):E763-74. National Institute of General Medical Sciences Stover T. Kester M. Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells. 2003 Nov. J Pharmacol Exp Ther. 307(2):468-75. National Heart, Lung, and Blood Institute Kester M. Kolesnick R. Sphingolipids as therapeutics. 2003 May. Pharmacol Res. 47(5):365-71. National Cancer Institute National Institute of Diabetes and Digestive and Kidney Diseases National Heart, Lung, and Blood Institute Bourbon NA. Sandirasegarane L. Kester M. Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest. 2002 Feb 1. J Biol Chem. 277(5):3286-92. National Institute of Diabetes and Digestive and Kidney Diseases National Heart, Lung, and Blood Institute Yun JK. Kester M. Regulatory role of sphingomyelin metabolites in hypoxia-induced vascular smooth muscle cell proliferation. 2002 Dec 1. Arch Biochem Biophys. 408(1):78-86. National Cancer Institute National Institute of Diabetes and Digestive and Kidney Diseases National Heart, Lung, and Blood Institute Bourbon NA. Yun J. Berkey D. Wang Y. Kester M. Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions. 2001 Jun. Am J Physiol Cell Physiol. 280(6):C1403-11. National Institute of Diabetes and Digestive and Kidney Diseases Sandirasegarane L. Kester M. Enhanced stimulation of Akt-3/protein kinase B-gamma in human aortic smooth muscle cells. 2001 Apr 27. Biochem Biophys Res Commun. 283(1):158-63. National Institute of Diabetes and Digestive and Kidney Diseases Kester M. Waybill P. Kozak M. New strategies to prevent restenosis. 2001. Am J Cardiovasc Drugs. 1(2):77-83. National Institute of Diabetes and Digestive and Kidney Diseases Bourbon NA. Yun J. Kester M. Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex. 2000 Nov 10. J Biol Chem. 275(45):35617-23. National Institute of Diabetes and Digestive and Kidney Diseases Sandirasegarane L. Charles R. Bourbon N. Kester M. NO regulates PDGF-induced activation of PKB but not ERK in A7r5 cells: implications for vascular growth arrest. 2000 Jul. Am J Physiol Cell Physiol. 279(1):C225-35. National Institute of Diabetes and Digestive and Kidney Diseases Charles R. Sandirasegarane L. Yun J. Bourbon N. Wilson R. Rothstein RP. Levison SW. Kester M. Ceramide-coated balloon catheters limit neointimal hyperplasia after stretch injury in carotid arteries. 2000 Aug 18. Circ Res. 87(4):282-8. National Institute of Diabetes and Digestive and Kidney Diseases