Michael F. Verderame All publications ( 49 ) Ongeri EM. Verderame MF. Hammond JM. The TATA binding protein associated factor 4b (TAF4b) mediates FSH stimulation of the IGFBP-3 promoter in cultured porcine ovarian granulosa cells. 2007 Nov 15. Mol Cell Endocrinol. 278(1-2):29-35. Cheng F. Zagon IS. Verderame MF. McLaughlin PJ. The opioid growth factor (OGF)-OGF receptor axis uses the p16 pathway to inhibit head and neck cancer. 2007 Nov 1. Cancer Res. 67(21):10511-8. Manni A. Rager T. Kimball SR. Jefferson LS. Washington S. Hu X. Verderame MF. Effects of alpha-difluoromethylornithine on thrombospondin-1 production by human breast cancer cells. 2007 Nov. Int J Oncol. 31(5):1187-91. McLaughlin PJ. Verderame MF. Hankins JL. Zagon IS. Overexpression of the opioid growth factor receptor downregulates cell proliferation of human squamous carcinoma cells of the head and neck. 2007 Mar. Int J Mol Med. 19(3):421-8. Jun JY. Griffith JW. Bruggeman R. Washington S. Demers LM. Verderame MF. Manni A. Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. 2007 Feb 27. Breast Cancer Res Treat. . Xu H. Washington S. Verderame MF. Manni A. Activation of protein kinase A (PKA) signaling mitigates the antiproliferative and antiinvasive effects of alpha-difluoromethylornithine in breast cancer cells. 2007 Feb 27. Breast Cancer Res Treat. . Zagon IS. Verderame MF. Hankins J. McLaughlin PJ. Overexpression of the opioid growth factor receptor potentiates growth inhibition in human pancreatic cancer cells. 2007 Apr. Int J Oncol. 30(4):775-83. Jun JY. Griffith JW. Bruggeman R. Washington S. Demers LM. Verderame MF. Manni A. Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. 2006 Dec 2. Breast Cancer Res Treat. . Zagon IS. Jaglowski JR. Verderame MF. Smith JP. Leure-Dupree AE. McLaughlin PJ. Combination chemotherapy with gemcitabine and biotherapy with opioid growth factor (OGF) enhances the growth inhibition of pancreatic adenocarcinoma. 2005 Nov. Cancer Chemother Pharmacol. 56(5):510-20. McLaughlin PJ. Jaglowski JR. Verderame MF. Stack BC. Leure-Dupree AE. Zagon IS. Enhanced growth inhibition of squamous cell carcinoma of the head and neck by combination therapy of paclitaxel and opioid growth factor. 2005 Mar. Int J Oncol. 26(3):809-16. Jaglowski JR. Zagon IS. Stack BC. Verderame MF. Leure-duPree AE. Manning JD. McLaughlin PJ. Opioid growth factor enhances tumor growth inhibition and increases the survival of paclitaxel-treated mice with squamous cell carcinoma of the head and neck. 2005 Jul. Cancer Chemother Pharmacol. 56(1):97-104. Zagon IS. Sassani JW. Verderame MF. McLaughlin PJ. Particle-mediated gene transfer of opioid growth factor receptor cDNA regulates cell proliferation of the corneal epithelium. 2005 Jul. Cornea. 24(5):614-9. National Eye Institute Ongeri EM. Verderame MF. Hammond JM. Follicle-stimulating hormone induction of ovarian insulin-like growth factor-binding protein-3 transcription requires a TATA box-binding protein and the protein kinase A and phosphatidylinositol-3 kinase pathways. 2005 Jul. Mol Endocrinol. 19(7):1837-48. National Institute of Child Health and Human Development Hu X. Washington S. Verderame MF. Manni A. Interaction between Polyamines and the Mitogen-Activated Protein Kinase Pathway in the Regulation of Cell Cycle Variables in Breast Cancer Cells. 2005 Dec 1. Cancer Res. 65(23):11026-33. National Cancer Institute Manni A. Washington S. Hu X. Griffith JW. Bruggeman R. Demers LM. Mauger D. Verderame MF. Effects of polyamine synthesis inhibitors on primary tumor features and metastatic capacity of human breast cancer cells. 2005. Clin Exp Metastasis. 22(3):255-63. National Cancer Institute Smith JP. Stanley WB. Verderame MF. Zagon IS. The functional significance of the cholecystokinin-C (CCK-C) receptor in human pancreatic cancer. 2004 Nov. Pancreas. 29(4):271-7. National Cancer Institute Smith JP. Verderame MF. Ballard EN. Zagon IS. Functional significance of gastrin gene expression in human cancer cells. 2004 Mar 15. Regul Pept. 117(3):167-73. National Cancer Institute Meehan WJ. Samant RS. Hopper JE. Carrozza MJ. Shevde LA. Workman JL. Eckert KA. Verderame MF. Welch DR. Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription. 2004 Jan 9. J Biol Chem. 279(2):1562-9. National Cancer Institute Hu X. Washington S. Verderame MF. Demers LM. Mauger D. Manni A. Biological activity of the S-adenosylmethionine decarboxylase inhibitor SAM486A in human breast cancer cells in vitro and in vivo. 2004 Dec. Int J Oncol. 25(6):1831-8. National Cancer Institute Ongeri EM. Zhu Q. Verderame MF. Hammond JM. Insulin-like growth factor-binding protein-3 in porcine ovarian granulosa cells: gene cloning, promoter mapping, and follicle-stimulating hormone regulation. 2004 Apr. Endocrinology. 145(4):1776-85. National Institute of Child Health and Human Development Manni A. Washington S. Mauger D. Hackett DA. Verderame MF. Cellular mechanisms mediating the anti-invasive properties of the ornithine decarboxylase inhibitor alpha-difluoromethylornithine (DFMO) in human breast cancer cells. 2004. Clin Exp Metastasis. 21(5):461-7. National Cancer Institute Zagon IS. Verderame MF. McLaughlin PJ. The expression and function of the OGF-OGFr axis - a tonically active negative regulator of growth - in COS cells. 2003 Oct. Neuropeptides. 37(5):290-7. Zagon IS. Essis FM. Verderame MF. Healy DA. Atnip RG. McLaughlin PJ. Opioid growth factor inhibits intimal hyperplasia in balloon-injured rat carotid artery. 2003 Mar. J Vasc Surg. 37(3):636-43. Manni A. Washington S. Craig L. Cloud M. Griffith JW. Verderame MF. Texter LJ. Mauger D. Demers LM. Harms JF. Welch DR. Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice. 2003. Clin Exp Metastasis. 20(4):321-5. National Cancer Institute Samant RS. Debies MT. Shevde LA. Verderame MF. Welch DR. Identification and characterization of the murine ortholog (brms1) of breast-cancer metastasis suppressor 1 (BRMS1). 2002 Jan 1. Int J Cancer. 97(1):15-20. National Cancer Institute Zagon IS. Verderame MF. McLaughlin PJ. The biology of the opioid growth factor receptor (OGFr). 2002 Feb. Brain Res Brain Res Rev. 38(3):351-76. National Cancer Institute National Eye Institute Smith JP. Verderame MF. McLaughlin P. Martenis M. Ballard E. Zagon IS. Characterization of the CCK-C (cancer) receptor in human pancreatic cancer. 2002 Dec. Int J Mol Med. 10(6):689-94. National Cancer Institute Manni A. Washington S. Griffith JW. Verderame MF. Mauger D. Demers LM. Samant RS. Welch DR. Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells. 2002. Clin Exp Metastasis. 19(2):95-105. National Cancer Institute Manni A. Trout D. Verderame MF. Washington S. Mauger D. Demers L. Effect of alpha-difluoromethyl-ornithine on the expression and function of the epidermal growth factor receptor in human breast epithelial cells in culture. 2001 Jul. Breast Cancer Res Treat. 68(2):139-46. National Cancer Institute Manni A. Fischer S. Franks M. Washington S. De Arment R. Griffith J. Demers L. Verderame M. Leiby B. Mauger D. S-adenosylmethionine decarboxylase overexpression reduces invasiveness and tumorigenicity in nude mice of MCF-7 breast cancer cells. 2001 Aug. Int J Oncol. 19(2):317-23. National Cancer Institute Zagon IS. Roesener CD. Verderame MF. Ohlsson-Wilhelm BM. Levin RJ. McLaughlin PJ. Opioid growth factor regulates the cell cycle of human neoplasias. 2000 Nov. Int J Oncol. 17(5):1053-61. National Cancer Institute Seraj MJ. Samant RS. Verderame MF. Welch DR. Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13. 2000 Jun 1. Cancer Res. 60(11):2764-9. National Cancer Institute Zagon IS. Verderame MF. Allen SS. McLaughlin PJ. Cloning, sequencing, chromosomal location, and function of cDNAs encoding an opioid growth factor receptor (OGFr) in humans. 2000 Feb 21. Brain Res. 856(1-2):75-83. National Cancer Institute Zagon IS. Verderame MF. Zimmer WE. McLaughlin PJ. Molecular characterization and distribution of the opioid growth factor receptor (OGFr) in mouse. 2000 Dec 8. Brain Res Mol Brain Res. 84(1-2):106-14. National Cancer Institute National Eye Institute Samant RS. Seraj MJ. Saunders MM. Sakamaki TS. Shevde LA. Harms JF. Leonard TO. Goldberg SF. Budgeon L. Meehan WJ. Winter CR. Christensen ND. Verderame MF. Donahue HJ. Welch DR. Analysis of mechanisms underlying BRMS1 suppression of metastasis. 2000. Clin Exp Metastasis. 18(8):683-93. National Cancer Institute Smith JP. Verderame MF. Zagon IS. Antisense oligonucleotides to gastrin inhibit growth of human pancreatic cancer. 1999 Jan 8. Cancer Lett. 135(1):107-12. National Cancer Institute Zagon IS. Verderame MF. Allen SS. McLaughlin PJ. Cloning, sequencing, expression and function of a cDNA encoding a receptor for the opioid growth factor, [Met(5)]enkephalin. 1999 Dec 4. Brain Res. 849(1-2):147-54. National Cancer Institute National Institute of Neurological Disorders and Stroke Smith JP. Hamory MW. Verderame MF. Zagon IS. Quantitative analysis of gastrin mRNA and peptide in normal and cancerous human pancreas. 1998 Sep. Int J Mol Med. 2(3):309-315. Manni A. Wechter R. Verderame MF. Mauger D. Cooperativity between the polyamine pathway and HER-2neu in transformation of human mammary epithelial cells in culture: role of the MAPK pathway. 1998 May 18. Int J Cancer. 76(4):563-70. National Cancer Institute Nelle TD. Verderame MF. Leis J. Wills JW. The major site of phosphorylation within the Rous sarcoma virus MA protein is not required for replication. 1998 Feb. J Virol. 72(2):1103-7. National Cancer Institute Verderame MF. pp60v-src transformation of rat cells but not chicken cells strongly correlates with low-affinity phosphopeptide binding by the SH2 domain. 1997 May. Mol Biol Cell. 8(5):843-54. National Cancer Institute Manni A. Wechter R. Gilmour S. Verderame MF. Mauger D. Demers LM. Ornithine decarboxylase over-expression stimulates mitogen-activated protein kinase and anchorage-independent growth of human breast epithelial cells. 1997 Jan 17. Int J Cancer. 70(2):175-82. National Cancer Institute Garnier L. Wills JW. Verderame MF. Sudol M. WW domains and retrovirus budding. 1996 Jun 27. Nature. 381(6585):744-5. Verderame MF. Nelle TD. Wills JW. The membrane-binding domain of the Rous sarcoma virus Gag protein. 1996 Apr. J Virol. 70(4):2664-8. National Cancer Institute Verderame MF. Guan JL. Woods Ignatoski KM. Transformation and pp60v-src autophosphorylation correlate with SHC-GRB2 complex formation in rat and chicken cells expressing host-range and kinase-active, transformation-defective alleles of v-src. 1995 Aug. Mol Biol Cell. 6(8):953-66. National Cancer Institute National Institute of General Medical Sciences Siever DA. Verderame MF. Identification of a complete Cek7 receptor protein tyrosine kinase coding sequence and cDNAs of alternatively spliced transcripts. 1994 Oct 21. Gene. 148(2):219-26. National Cancer Institute Woods KM. Verderame MF. Autophosphorylation is required for high kinase activity and efficient transformation ability of proteins encoded by host range alleles of v-src. 1994 Nov. J Virol. 68(11):7267-74. National Cancer Institute Verderame MF. Varmus HE. Highly conserved amino acids in the SH2 and catalytic domains of v-src are altered in naturally occurring, transformation-defective alleles. 1994 Jan. Oncogene. 9(1):175-82. National Cancer Institute Serra R. Verderame MF. Isom HC. Transforming growth factor beta 1 partially suppresses the transformed phenotype of ras-transformed hepatocytes. 1992 Oct. Cell Growth Differ. 3(10):693-704. National Cancer Institute