Richard Frisque All publications ( 31 ) Tyagarajan SK. Frisque RJ. Stability and function of JC virus large T antigen and T' proteins are altered by mutation of their phosphorylated threonine 125 residues. 2006 Mar. J Virol. 80(5):2083-91. National Institute of Neurological Disorders and Stroke Bollag B. Kilpatrick LH. Tyagarajan SK. Tevethia MJ. Frisque RJ. JC virus T'135, T'136 and T'165 proteins interact with cellular p107 and p130 in vivo and influence viral transformation potential. 2006 Dec. J Neurovirol. 12(6):428-42. National Cancer Institute National Institute of Neurological Disorders and Stroke Frisque RJ. Hofstetter C. Tyagarajan SK. Transforming activities of JC virus early proteins. 2006. Adv Exp Med Biol. 577:288-309. National Institute of Neurological Disorders and Stroke Frisque RJ. Bollag B. Tyagarajan SK. Kilpatrick LH. T' proteins influence JC virus biology. 2003. J Neurovirol. 9 Suppl 1:15-20. National Institute of Neurological Disorders and Stroke Prins C. Frisque RJ. JC virus T' proteins encoded by alternatively spliced early mRNAs enhance T antigen-mediated viral DNA replication in human cells. 2001 Jun. J Neurovirol. 7(3):250-64. National Cancer Institute Frisque RJ. Structure and function of JC virus T' proteins. 2001 Aug. J Neurovirol. 7(4):293-7. National Cancer Institute Chatterjee M. Weyandt TB. Frisque RJ. Identification of archetype and rearranged forms of BK virus in leukocytes from healthy individuals. 2000 Mar. J Med Virol. 60(3):353-62. National Cancer Institute Bollag B. Prins C. Snyder EL. Frisque RJ. Purified JC virus T and T' proteins differentially interact with the retinoblastoma family of tumor suppressor proteins. 2000 Aug 15. Virology. 274(1):165-78. National Cancer Institute Newman JT. Frisque RJ. Identification of JC virus variants in multiple tissues of pediatric and adult PML patients. 1999 May. J Med Virol. 58(1):79-86. National Cancer Institute Newman JS. Baskin GB. Frisque RJ. Identification of SV40 in brain, kidney and urine of healthy and SIV-infected rhesus monkeys. 1998 Aug. J Neurovirol. 4(4):394-406. National Cancer Institute National Center for Research Resources Frisque RJ. Rearranged and chimaeric primate polyomavirus genomes. 1998. Dev Biol Stand. 94:103-13. National Cancer Institute Newman JT. Frisque RJ. Detection of archetype and rearranged variants of JC virus in multiple tissues from a pediatric PML patient. 1997 Jul. J Med Virol. 52(3):243-52. National Cancer Institute Daniel AM. Swenson JJ. Mayreddy RP. Khalili K. Frisque RJ. Sequences within the early and late promoters of archetype JC virus restrict viral DNA replication and infectivity. 1996 Feb 1. Virology. 216(1):90-101. National Cancer Institute Bollag B. Mackeen PC. Frisque RJ. Purified JC virus T antigen derived from insect cells preferentially interacts with binding site II of the viral core origin under replication conditions. 1996 Apr 1. Virology. 218(1):81-93. National Cancer Institute Swenson JJ. Trowbridge PW. Frisque RJ. Replication activity of JC virus large T antigen phosphorylation and zinc finger domain mutants. 1996 Apr. J Neurovirol. 2(2):78-86. National Cancer Institute Swenson JJ. Frisque RJ. Biochemical characterization and localization of JC virus large T antigen phosphorylation domains. 1995 Oct 1. Virology. 212(2):295-308. National Cancer Institute Trowbridge PW. Frisque RJ. Identification of three new JC virus proteins generated by alternative splicing of the early viral mRNA. 1995 Jun. J Neurovirol. 1(2):195-206. National Cancer Institute Lynch KJ. Haggerty S. Frisque RJ. DNA replication of chimeric JC virus-simian virus 40 genomes. 1994 Nov 1. Virology. 204(2):819-22. National Cancer Institute Tavis JE. Trowbridge PW. Frisque RJ. Converting the JCV T antigen Rb binding domain to that of SV40 does not alter JCV's limited transforming activity but does eliminate viral viability. 1994 Mar. Virology. 199(2):384-92. National Cancer Institute Trowbridge PW. Frisque RJ. Analysis of G418-selected Rat2 cells containing prototype, variant, mutant, and chimeric JC virus and SV40 genomes. 1993 Oct. Virology. 196(2):458-74. National Cancer Institute Daniel AM. Frisque RJ. Transcription initiation sites of prototype and variant JC virus early and late messenger RNAs. 1993 May. Virology. 194(1):97-109. National Cancer Institute Bollag B. Frisque RJ. PAb 2000 specifically recognizes the large T and small t proteins of JC virus. 1992 Sep 15. Virus Res. 25(3):223-39. National Cancer Institute White FA. Ishaq M. Stoner GL. Frisque RJ. JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy. 1992 Oct. J Virol. 66(10):5726-34. National Cancer Institute Deckhut AM. Tevethia MJ. Haggerty S. Frisque RJ. Tevethia SS. Localization of common cytotoxic T lymphocyte recognition epitopes on simian papovavirus SV40 and human papovavirus JC virus T antigens. 1991 Jul. Virology. 183(1):122-32. National Cancer Institute Tavis JE. Frisque RJ. Altered DNA binding and replication activities of JC virus T-antigen mutants. 1991 Jul. Virology. 183(1):239-50. National Cancer Institute Lynch KJ. Frisque RJ. Factors contributing to the restricted DNA replicating activity of JC virus. 1991 Jan. Virology. 180(1):306-17. National Cancer Institute Tavis JE. Frisque RJ. Walker DL. White FA. Antigenic and transforming properties of the DB strain of the human polyomavirus BK virus. 1990 Oct. Virology. 178(2):568-72. National Institute of Allergy and Infectious Diseases National Cancer Institute Lynch KJ. Frisque RJ. Identification of critical elements within the JC virus DNA replication origin. 1990 Dec. J Virol. 64(12):5812-22. National Cancer Institute Myers C. Frisque RJ. Arthur RR. Direct isolation and characterization of JC virus from urine samples of renal and bone marrow transplant patients. 1989 Oct. J Virol. 63(10):4445-9. National Cancer Institute Tavis JE. Walker DL. Gardner SD. Frisque RJ. Nucleotide sequence of the human polyomavirus AS virus, an antigenic variant of BK virus. 1989 Feb. J Virol. 63(2):901-11. National Institute of Allergy and Infectious Diseases National Cancer Institute Bollag B. Chuke WF. Frisque RJ. Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation. 1989 Feb. J Virol. 63(2):863-72. National Cancer Institute