Targeted Transgenesis and Transgene Expression: Stem Cell Differentiation/Osteogenesis

Dr. Bronson is Director of the Diabetic Retinopathy Animal Models Core and project team member for the Penn State University Juvenile Diabetes Research Foundation Diabetic Retinopathy Center, and is Director of the Summer Undergraduate Research Internship Program. Dr. Bronson has nearly 20 years of experience in generating and studying genetically altered mice as models for understanding and treating human disease. She is known for the creation of targeted transgenic lines, where small recombinant transgenic sequences as well as bacterial artificial chromosome-based transgenic sequences are introduced in a single-copy at the X-linked Hypoxanthine Phosphoribosyl Transferase (HPRT) locus by a directly selectable homologous recombination event in murine embryonic stem cells. Dr. Bronson's research interests include stem cell differentiation, osteogenesis, and diabetic retinopathy.