Willard Freeman All publications ( 25 ) Lull ME. Carkaci-Salli N. Freeman WM. Myers JL. Midgley FM. Thomas NJ. Kimatian SJ. Vrana KE. Undar A. Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. 2008 Feb 27. Pediatr Res. . Freeman WM. Patel KM. Brucklacher RM. Lull ME. Erwin M. Morgan D. Roberts DC. Vrana KE. Persistent Alterations in Mesolimbic Gene Expression with Abstinence from Cocaine Self-Administration. 2007 Sep 12. Neuropsychopharmacology. . Bowyer JF. Pogge AR. Delongchamp RR. O'Callaghan JP. Patel KM. Vrana KE. Freeman WM. A threshold neurotoxic amphetamine exposure inhibits parietal cortex expression of synaptic plasticity-related genes. 2007 Jan 5. Neuroscience. 144(1):66-76. Lull ME. Freeman WM. Myers JL. Midgley F. Kimatian SJ. Undar A. Vrana KE. Plasma proteomics: a noninvasive window on pathology and pediatric cardiac surgery. 2006 Sep-Oct. ASAIO J. 52(5):562-6. Antonetti DA. Barber AJ. Bronson SK. Freeman WM. Gardner TW. Jefferson LS. Kester M. Kimball SR. Krady JK. LaNoue KF. Norbury CC. Quinn PG. Sandirasegarane L. Simpson IA. JDRF Diabetic Retinopathy Center Group. Diabetic retinopathy: seeing beyond glucose-induced microvascular disease. 2006 Sep. Diabetes. 55(9):2401-11. National Eye Institute Freeman WM. Gooch RS. Lull ME. Worst TJ. Walker SJ. Xu AS. Green H. Pierre PJ. Grant KA. Vrana KE. Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration. 2006 May-Jun. Alcohol Alcohol. 41(3):300-5. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Freeman WM. Lull ME. Guilford MT. Vrana KE. Depletion of abundant proteins from non-human primate serum for biomarker studies. 2006 May. Proteomics. 6(10):3109-13. National Institute on Drug Abuse Worst TJ. Tan JC. Robertson DJ. Freeman WM. Hyytia P. Kiianmaa K. Vrana KE. Transcriptome analysis of frontal cortex in alcohol-preferring and nonpreferring rats. 2005 May 15. J Neurosci Res. 80(4):529-38. Freeman WM. Brebner K. Amara SG. Reed MS. Pohl J. Phillips AG. Distinct proteomic profiles of amphetamine self-administration transitional states. 2005. Pharmacogenomics J. 5(3):203-14. National Institute on Drug Abuse Stredrick DL. Stokes AH. Worst TJ. Freeman WM. Johnson EA. Lash LH. Aschner M. Vrana KE. Manganese-induced cytotoxicity in dopamine-producing cells. 2004 Jun. Neurotoxicology. 25(4):543-53. Walker SJ. Worst TJ. Freeman WM. Vrana KE. Functional genomic analysis in pain research using hybridization arrays. 2004. Methods Mol Med. 99:239-53. Vrana KE. Freeman WM. Aschner M. Use of microarray technologies in toxicology research. 2003 Jun. Neurotoxicology. 24(3):321-32. National Institute on Drug Abuse Agency for Health Care Policy and Research Worst TJ. Freeman WM. Walker SJ. Vrana KE. Systematic screening of gene expression using a cDNA macroarray. 2003. Methods Mol Med. 79:243-59. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Freeman WM. Brebner K. Patel KM. Lynch WJ. Roberts DC. Vrana KE. Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression. 2002 Oct. Neurochem Res. 27(10):1181-92. National Institute on Drug Abuse Freeman WM. Dougherty KE. Vacca SE. Vrana KE. An interactive database of cocaine-responsive gene expression. 2002 Mar 12. ScientificWorldJournal. 2:701-6. Freeman WM. Brebner K. Lynch WJ. Patel KM. Robertson DJ. Roberts DC. Vrana KE. Changes in rat frontal cortex gene expression following chronic cocaine. 2002 Jul 15. Brain Res Mol Brain Res. 104(1):11-20. National Institute on Drug Abuse Stokes AH. Freeman WM. Mitchell SG. Burnette TA. Hellmann GM. Vrana KE. Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity. 2002 Dec. Neurotoxicology. 23(6):675-84. National Institute on Drug Abuse National Institute of General Medical Sciences Freeman WM. Nader MA. Nader SH. Robertson DJ. Gioia L. Mitchell SM. Daunais JB. Porrino LJ. Friedman DP. Vrana KE. Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression. 2001 Apr. J Neurochem. 77(2):542-9. National Institute on Drug Abuse Freeman WM. Brebner K. Lynch WJ. Robertson DJ. Roberts DC. Vrana KE. Cocaine-responsive gene expression changes in rat hippocampus. 2001. Neuroscience. 108(3):371-80. National Institute on Drug Abuse Freeman WM. Robertson DJ. Vrana KE. Fundamentals of DNA hybridization arrays for gene expression analysis. 2000 Nov. Biotechniques. 29(5):1042-6, 1048-55. National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Freeman WM. Yohrling GJ. Daunais JB. Gioia L. Hart SL. Porrino LJ. Davies HM. Vrana KE. A cocaine analog, 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway. 2000 Dec 22. Drug Alcohol Depend. 61(1):15-21. National Institute on Drug Abuse Freeman WM. Walker SJ. Vrana KE. Quantitative RT-PCR: pitfalls and potential. 1999 Jan. Biotechniques. 26(1):112-22, 124-5. National Institute on Drug Abuse Gioia L. Vogt LJ. Freeman WM. Flood A. Vogt BA. Vrana KE. PCR-based apolipoprotein E genotype analysis from archival fixed brain. 1998 Apr 30. J Neurosci Methods. 80(2):209-14. National Institute on Aging National Institute on Drug Abuse National Institute of Mental Health Xu Y. Stokes AH. Freeman WM. Kumer SC. Vogt BA. Vrana KE. Tyrosinase mRNA is expressed in human substantia nigra. 1997 Apr. Brain Res Mol Brain Res. 45(1):159-62. National Institute on Aging National Institute of General Medical Sciences National Institute on Drug Abuse Freeman WM. Vrana SL. Vrana KE. Use of elevated reverse transcription reaction temperatures in RT-PCR. 1996 May. Biotechniques. 20(5):782-3. National Institute on Drug Abuse