Extending Pummerer reaction chemistry. Application to the oxidative cyclization of tryptophan derivatives.
Journal
Organic letters.
Citation
Org Lett
. 6(17):2849-52
Publication date
2004 Aug 19
Authors
Feldman KS
Karatjas AG
Grant agencies
National Institute of General Medical Sciences
Grants
NIGMS GM35727
Abstract
The diastereoselective oxidative cyclization of a beta-oxygenated tryptophan derivative is reported. This process, which utilizes a new variant of the Pummerer reaction, may have application in TMC-95A synthesis.