A repeated measures concordance correlation coefficient.
Journal
  Statistics in medicine.
Citation
  Stat Med. 26(16):3095-113
Publication date
  2007 Jul 20
Authors
  King TS
Chinchilli VM
Carrasco JL
Investigators
  Vernon M. Chinchilli
Tonya S. King
MeSH headings
  Models, Statistical
Phlebotomy
Sensitivity and Specificity
MeSH qualifiers
  statistics & numerical data
Abstract
  The concordance correlation coefficient is commonly used to assess agreement between two raters or two methods of measuring a response when the data are measured on a continuous scale. However, the situation may arise in which repeated measurements are taken for each rater or method, e.g. longitudinal studies in clinical trials or bioassay data with subsamples. This paper proposes a coefficient for measuring agreement between two raters or two methods of measuring a response in the presence of repeated measurements. We illustrate the methodology with examples comparing (1) 1-hr versus 2-hr blood draws for measuring cortisol in an asthma clinical trial and (2) two measurements of percentage body fat, from skinfold calipers and dual energy X-ray absorptiometry.